SCHEMBL1999570

SCHEMBL1999570

CCCC([N+](=O)[O-])[N+](=O)[O-]

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.42
TSHR P16473 3/20 0.40
CYP3A4 P08684 2/20 0.36
NFKB1 P19838 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
HPGD P15428 1/20 0.33
HIF1A Q16665 1/20 0.33
SLC6A3 Q01959 2/20 0.32
CHRM1 P11229 1/20 0.32
AKR1A1 P14550 1/20 0.32
CHRM3 P20309 1/20 0.32
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
ADRA1A P35348 1/20 0.32
HRH1 P35367 1/20 0.32
DRD3 P35462 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
SLC6A2 P23975 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9452613 0.83 ALDH1A1 (0.46) ALDH1A1TSHRFDPS
SCHEMBL9323781 0.81 ALDH1A1 (0.46) ALDH1A1NFKB1FDPS
SCHEMBL7867816 0.79 ALDH1A1 (0.50) ALDH1A1TSHRFDPS
SCHEMBL1170239 0.77 ALDH1A1 (0.42) ALDH1A1TSHRCYP3A4NFKB1NPSR1
SCHEMBL9452624 0.75
SCHEMBL267634 0.74
SCHEMBL16907336 0.74
SCHEMBL7988566 0.74
SCHEMBL8931943 0.72
SCHEMBL2799449 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119390948-A Silicofluorene pterene aromatic ether amine copolymer fluorescent probe and preparation method and application thereof 湖南华南光电科技股份有限公司 2025-02-07 CN disclosed
CN-103282769-A Water quality monitoring apparatus MIKASA SHOJI CO LTD 2013-09-04 CN disclosed
US-H2257-H1 Microtags for detection and identification of materials THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2011-06-07 US disclosed
US-7713401-B2 Methods for performing electrochemical nitration reactions BATTELLE ENERGY ALLIANCE, LLC (US) 2010-05-11 US disclosed
US-20090038953-A1 METHODS FOR PERFORMING ELECTROCHEMICAL NITRATION REACTIONS ENERGY, UNITED STATES DEPARTMENT OF 2009-02-12 US disclosed
WO-2009020798-A1 METHODS FOR PERFORMING ELECTROCHEMICAL NITRATION REACTIONS BATTELLE ENERGY ALLIANCE, LLC (US) 2009-02-12 WO disclosed
US-20070072197-A1 Microtags for detection and identification of materials NAVY, UNITED STATES OF AMERICA, REPRESENTED BY SEC. OF 2007-03-29 US disclosed
US-20040005676-A1 Biocatalytic reduction of nitro groups DIVERSA CORPORATION 2004-01-08 US disclosed
US-4910322-A Synthesis of geminal dinitro compounds THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1990-03-20 US disclosed
US-4774366-A Synthesis of geminal dinitro compounds THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1988-09-27 US disclosed
US-4594430-A Synthesis of geminal dinitro compounds UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1986-06-10 US disclosed
US-4297501-A BY REACTING PRIMARY AMINES, CARBON MONOXIDE AND AN ORGANIC ALCOHOL IN THE PRESENCE OF OXYGEN AND A METAL CATALYST SYSTEM BAYER AKTIENGESELLSCHAFT (DE) 1981-10-27 US disclosed