⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2800523 | 0.87 | — | — | |
| SCHEMBL2802985 | 0.78 | — | — | |
| SCHEMBL11532788 | 0.76 | — | — | |
| SCHEMBL1170239 | 0.72 | ALDH1A1 (0.42) | — | |
| SCHEMBL1999570 | 0.72 | ALDH1A1 (0.42) | — | |
| SCHEMBL267634 | 0.70 | — | — | |
| SCHEMBL7988566 | 0.70 | — | — | |
| SCHEMBL16907336 | 0.70 | — | — | |
| SCHEMBL1151111 | 0.70 | ALDH1A1 (0.42) | — | |
| SCHEMBL2801476 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676702-B2 | Methods for synthesizing amatoxin building block and amatoxins | HEIDELBERG PHARMA GMBH (DE) | 2017-06-13 | — | — | US | claimed |
| US-9630907-B2 | — | — | 2017-04-25 | — | — | US | claimed |
| EP-2872479-B1 | METHODS FOR SYNTHESIZING AMATOXIN BUILDING BLOCK AND AMATOXINS | HEIDELBERG PHARMA GMBH (DE) | 2016-06-08 | — | — | EP | claimed |
| US-20150210628-A1 | METHODS FOR SYNTHESIZING AMATOXIN BUILDING BLOCK AND AMATOXINS | HEIDELBERG PHARMA GMBH (DE) | 2015-07-30 | — | — | US | claimed |
| EP-2872479-A1 | METHODS FOR SYNTHESIZING AMATOXIN BUILDING BLOCK AND AMATOXINS | Heidelberg Pharma GmbH (DE) | 2015-05-20 | — | — | EP | claimed |
| WO-2014009025-A1 | METHODS FOR SYNTHESIZING AMATOXIN BUILDING BLOCK AND AMATOXINS | HEIDELBERG PHARMA GMBH (DE) | 2014-01-16 | — | — | WO | claimed |
| EP-2684865-A1 | Methods for synthesizing amatoxin building block and amatoxins | Heidelberg Pharma GmbH (DE) | 2014-01-15 | — | — | EP | claimed |
| CN-1078590-C | Process for preparing 2-oxindoles and N-hydroxy-2-oxindoles | CATALYTICA INC (US) | 2002-01-30 | — | — | CN | claimed |
| CN-1177347-A | Process for preparing 2 -oxindoles and N -hydroxy -2 -oxindoles | CATALYTICA INC (US) | 1998-03-25 | — | — | CN | claimed |
| US-5604294-A | IMMUNOSUPRESSIVE, ANTIMICROBIAL, ANTIFUNGAL, ANTIVIRAL, ANTI-INFLAMMATORY AND ANTIPROLIFERATIVE ACTIVITY | ABBOTT LABORATORIES | 1997-02-18 | — | — | US | claimed |
| WO-1994021635-A1 | MACROCYCLIC IMMUNOMODULATORS | ABBOTT LABORATORIES (US) | 1994-09-29 | — | — | WO | claimed |
| US-8404860-B2 | Compound having hydantoin ring and method of producing the same | TOKUYAMA CORPORATION (JP) | 2013-03-26 | — | — | US | disclosed |
| US-20120289705-A1 | COMPOUND HAVING HYDANTOIN RING AND METHOD OF PRODUCING THE SAME | SHIIGI HIROFUMI (JP) | 2012-11-15 | — | — | US | disclosed |
| US-8258313-B2 | Compound having hydantoin ring and method of producing the same | TOKUYAMA CORPORATION (JP) | 2012-09-04 | — | — | US | disclosed |
| US-20100184993-A1 | COMPOUND HAVING HYDANTOIN RING AND METHOD OF PRODUCING THE SAME | TOKUYAMA CORPORATION (JP) | 2010-07-22 | — | — | US | disclosed |
| US-4600793-A | Process for the preparation of urethanes | CATALYTICA ASSOCIATES (US) | 1986-07-15 | — | — | US | disclosed |
| EP-0157828-A1 | PROCESS FOR THE PREPARATION OF URETHANES. | CATALYTICA ASSOCIATES (US) | 1985-10-16 | — | — | EP | disclosed |
| WO-1985001285-A1 | PROCESS FOR THE PREPARATION OF URETHANES | CATALYTICA ASSOCIATES (US) | 1985-03-28 | — | — | WO | disclosed |
| US-4476290-A | Photocurable silicon compound composition | TOKYO SHIBAURA DENKI KABUSHIKI KAISHA (JP) | 1984-10-09 | — | — | US | disclosed |
| EP-0104590-A1 | Photocurable silicon compound composition | KABUSHIKI KAISHA TOSHIBA (JP) | 1984-04-04 | — | — | EP | disclosed |