SCHEMBL19995977

SCHEMBL19995977

C=C(C)C(=O)OCCCC1([SiH](C)C)CCCCO1

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
POLB P06746 1/20 0.39
APEX1 P27695 1/20 0.39
HTT P42858 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
THRB P10828 1/20 0.36
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6358698 0.83 ALDH1A1 (0.37) TSHRPOLBAPEX1HTTTDP1
SCHEMBL27907168 0.78 TSHR (0.46) TSHRPOLBAPEX1HTTTDP1
SCHEMBL28586887 0.77 LMNA (0.32) TSHRALDH1A1
SCHEMBL28430957 0.77 TSHR (0.45) TSHRPOLBAPEX1HTTTDP1
SCHEMBL27637466 0.76 TSHR (0.44) TSHRPOLBAPEX1HTTTDP1
SCHEMBL21110931 0.76 TSHR (0.46) TSHRPOLBAPEX1HTTTDP1
SCHEMBL1617411 0.75 MEN1 (0.35) TSHRHTTTHRB
SCHEMBL28895351 0.75
SCHEMBL29136240 0.74 TSHR (0.42) TSHRPOLBAPEX1HTTTDP1
SCHEMBL15268465 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200071525-A1 PDMS RESIN FOR STEREOLITHOGRAPHIC 3D-PRINTING OF PDMS UNIVERSITY OF WASHINGTON (US) 2020-03-05 US claimed
WO-2018058135-A1 PDMS RESIN FOR STEREOLITHOGRAPHIC 3D-PRINTING OF PDMS UNIVERSITY OF WASHINGTON (US) 2018-03-29 WO claimed
CN-111344874-B Thermoelectric conversion device 株式会社朝日精细橡胶研究所 2024-10-22 CN disclosed
CN-112040936-B Transdermal therapeutic system for transdermal administration of solifenacin 罗曼治疗系统股份公司 2024-07-23 CN disclosed
CN-111447926-B Transdermal therapeutic system for transdermal administration of guanfacine comprising at least one additive 罗曼治疗系统股份公司 2024-04-30 CN disclosed
CN-117467117-A Organic silicon modified epoxy resin, preparation method thereof and packaging material 深圳市华星光电半导体显示技术有限公司 2024-01-30 CN disclosed
US-20200071525-A1 PDMS RESIN FOR STEREOLITHOGRAPHIC 3D-PRINTING OF PDMS UNIVERSITY OF WASHINGTON (US) 2020-03-05 US disclosed
WO-2018058135-A1 PDMS RESIN FOR STEREOLITHOGRAPHIC 3D-PRINTING OF PDMS UNIVERSITY OF WASHINGTON (US) 2018-03-29 WO disclosed