SCHEMBL6358698

SCHEMBL6358698

C=C(C)C(=O)OCC1([SiH](C)C)CCCCO1

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.37
TSHR P16473 3/20 0.35
THRB P10828 1/20 0.33
POLB P06746 1/20 0.31
APEX1 P27695 1/20 0.31
HTT P42858 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19995977 0.83 TSHR (0.44) ALDH1A1TSHRTHRBPOLBAPEX1
SCHEMBL9798413 0.82 TSHR (0.36) ALDH1A1TSHR
SCHEMBL27782756 0.76 ALDH1A1 (0.39) ALDH1A1TSHRTHRB
SCHEMBL5281867 0.73 ALDH1A1 (0.42) ALDH1A1TSHRTHRBPOLBAPEX1
SCHEMBL3797298 0.73
SCHEMBL28586887 0.73 LMNA (0.32) ALDH1A1TSHR
SCHEMBL4122914 0.72 TSHR (0.44) ALDH1A1TSHRTHRBPOLBAPEX1
SCHEMBL2878361 0.72 ALDH1A1 (0.41) ALDH1A1TSHRTHRB
SCHEMBL25260436 0.71
SCHEMBL27464393 0.71 CYP2C19 (0.37) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104497528-A Modified PC/ABS (polycarbonate/acrylonitrile-butadiene-styrene) engineering plastic SUZHOU NEW DISTR JIAHE PLASTIC CO LTD 2015-04-08 CN claimed
CN-115674498-A Method for recycling and reusing plastic 广东瑞远新材料有限公司 2023-02-03 CN disclosed
CN-104059366-B Composition for controlled assembling and the improved ordering of silicon-containing block-copolymer 加利福尼亚大学董事会 2018-02-09 CN disclosed
CN-104829847-A Junction-functionalized block copolymers UNIV CALIFORNIA 2015-08-12 CN disclosed
CN-104497528-A Modified PC/ABS (polycarbonate/acrylonitrile-butadiene-styrene) engineering plastic SUZHOU NEW DISTR JIAHE PLASTIC CO LTD 2015-04-08 CN disclosed
CN-104059366-A Compositions For Controlled Assembly And Improved Ordering Of Silicon-containing Block Copolymers UNIV CALIFORNIA 2014-09-24 CN disclosed
US-6939510-B2 Anti-protista preparation WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2005-09-06 US disclosed
EP-1149531-B1 Anti-protista preparation WAKO PURE CHEM IND LTD (JP) 2004-06-30 EP disclosed
US-20010048916-A1 Anti-protista preparation WAKO PURE CHEMICAL INDUSTRIES, LTD (JP) 2001-12-06 US disclosed
EP-1149531-A1 Anti-protista preparation Wako Pure Chemical Industries, Ltd. (JP) 2001-10-31 EP disclosed