Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL20984762 | 0.98 | ALOX15 (0.41) | ALOX15MAPK1ALDH1A1HSP90AA1TLR9 | |
| Hydrochloric Acid SCHEMBL31082749 | 0.98 | ALOX15 (0.41) | ALOX15MAPK1ALDH1A1HSP90AA1TLR9 | |
| Hydrochloric Acid SCHEMBL7823944 | 0.98 | ALOX15 (0.41) | ALOX15MAPK1ALDH1A1HSP90AA1TLR9 | |
| Sulfuric Acid SCHEMBL20984468 | 0.88 | CA2 (0.41) | ALOX15ALDH1A1HSP90AA1TLR9MEN1 | |
| Phosphoric Acid SCHEMBL20984888 | 0.88 | NPC1 (0.41) | ALOX15ALDH1A1HSP90AA1TLR9L3MBTL1 | |
| Oxalic Acid SCHEMBL20984934 | 0.88 | ALDH1A1 (0.44) | ALOX15ALDH1A1HSP90AA1TLR9MEN1 | |
| Nitric Acid SCHEMBL20984071 | 0.84 | MEN1 (0.37) | ALOX15MAPK1ALDH1A1HSP90AA1TLR9 | |
| SCHEMBL9983346 | 0.80 | HSP90AA1 (0.41) | ALOX15MAPK1ALDH1A1HSP90AA1TLR9 | |
| SCHEMBL11796056 | 0.79 | ALOX15 (0.46) | ALOX15MAPK1ALDH1A1HSP90AA1TLR9 | |
| SCHEMBL15423725 | 0.79 | ALOX15 (0.46) | ALOX15MAPK1ALDH1A1HSP90AA1TLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105503939-B | O-methoxy phenylhydrazone double-core titanium complex and its preparation method and application | 山西大学 | 2017-12-05 | — | — | CN | claimed |
| CN-105503939-A | O-methoxy phenylhydrazone dicaryon metal complex and preparation method and application thereof | UNIV SHANXI | 2016-04-20 | — | — | CN | claimed |
| CN-112409203-B | Method for simultaneously synthesizing phenylhydrazine salt and pyruvic acid or glyoxylic acid | 帕潘纳(北京)科技有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-112409203-A | Method for simultaneously synthesizing phenylhydrazine salt and pyruvic acid or glyoxylic acid | 帕潘纳(北京)科技有限公司 | 2021-02-26 | — | — | CN | disclosed |
| CN-107663161-A | A kind of continuous stream synthesis technique of phenylhydrazine salt and substituted benzene hydrazonium salt | 上海惠和化德生物科技有限公司 | 2018-02-06 | — | — | CN | disclosed |
| CN-105503939-B | O-methoxy phenylhydrazone double-core titanium complex and its preparation method and application | 山西大学 | 2017-12-05 | — | — | CN | disclosed |
| CN-105503939-A | O-methoxy phenylhydrazone dicaryon metal complex and preparation method and application thereof | UNIV SHANXI | 2016-04-20 | — | — | CN | disclosed |
| CN-103396428-B | Zirconium metal complex of furan aldehyde (ketone) hydrazone as well as preparation method and application of zirconium metal complex | UNIV SHANXI | 2015-04-15 | — | — | CN | disclosed |
| CN-103396428-A | Zirconium metal complex of furan aldehyde (ketone) hydrazone as well as preparation method and application of zirconium metal complex | UNIV SHANXI | 2013-11-20 | — | — | CN | disclosed |
| US-20110269763-A1 | CRTH2 receptor ligands for medicinal uses | 7TM PHARMA A/S (DK) | 2011-11-03 | — | — | US | disclosed |
| US-8022063-B2 | CRTH2 receptor ligands for medicinal uses | 7TM PHARMA A/S (DK) | 2011-09-20 | — | — | US | disclosed |
| CN-1980664-A | CRTH2 receptor ligands for therapeutic use | 7TM PHARMA AS (DK) | 2007-06-13 | — | — | CN | disclosed |
| EP-1758579-A1 | CRTH2 RECEPTOR LIGANDS FOR MEDICINAL USES | 7TM Pharma A/S (DK) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005115382-A1 | CRTH2 RECEPTOR LIGANDS FOR MEDICINAL USES | 7TM PHARMA A/S (DK) | 2005-12-08 | — | — | WO | disclosed |
| CN-1148340-A | Treatment of 5HTZBMethods of receptor-related disorders | LILLY CO ELI (US) | 1997-04-23 | — | — | CN | disclosed |
| US-4017540-A | INSECTICIDES, MITICIDES | THE UPJOHN COMPANY (US) | 1977-04-12 | — | — | US | disclosed |
| US-4014932-A | ANTHELMINTICS, PESTICIDES, MITICIDES, INSECTICIDES | THE UPJOHN COMPANY (US) | 1977-03-29 | — | — | US | disclosed |
| US-3987234-A | ACRYLIC ESTER POLYMERS | HENKEL & CIE G.M.B.H. (DT) | 1976-10-19 | — | — | US | disclosed |
| US-3932661-A | Anthelmintic methods employing benzoyl chloride phenylhydrazones | THE UPJOHN COMPANY (US) | 1976-01-13 | — | — | US | disclosed |
| US-3931318-A | ANTHELMINTICS, PESTICIDES | THE UPJOHN COMPANY (US) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269763-A1 | CRTH2 receptor ligands for medicinal uses | HRH1, HRH2, HRH4 | ALOX15 283/4885MAPK1 1317/4885ALDH1A1 505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.