Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SLC22A12 | Q96S37 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16492688 | 0.80 | KMT2A (0.58) | KMT2AMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13565375 | 0.79 | SCD (0.43) | KMT2AMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL21104478 | 0.79 | MCL1 (0.40) | KMT2AMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10116480 | 0.78 | SMN1; SMN2 (0.59) | GAAPOLBMAPK1ALDH1A1LMNA | |
| SCHEMBL22455897 | 0.78 | SLC22A12 (0.49) | SLC22A12NR3C1 | |
| SCHEMBL19303635 | 0.77 | PSIP1 (0.61) | KMT2AMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL20290538 | 0.77 | KMT2A (0.55) | KMT2AMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14830619 | 0.77 | PSIP1 (0.59) | KMT2AMEN1TSHRGAAPOLB | |
| SCHEMBL13564954 | 0.75 | GRIA1 (0.50) | KMT2AMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13469116 | 0.75 | ALDH1A1 (0.50) | KMT2AMEN1TSHRGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9926309-B2 | Pi-kinase inhibitors with anti-infective activity | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2018-03-27 | — | — | US | disclosed |