Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 15/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13565494 | 0.84 | SCD (0.44) | SCDKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL13565912 | 0.83 | PSIP1 (0.44) | PPARAGAA | |
| SCHEMBL13565061 | 0.83 | PPARA (0.43) | PPARA | |
| SCHEMBL19997239 | 0.79 | KMT2A (0.54) | KMT2APOLBMAPK1MEN1CYP1A2 | |
| SCHEMBL13565993 | 0.79 | PPARA (0.55) | PPARA | |
| SCHEMBL13565062 | 0.79 | PPARA (0.44) | PPARACYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL13565602 | 0.79 | SLC22A12 (0.44) | PPARA | |
| SCHEMBL17090293 | 0.79 | KIF11 (0.48) | PPARA | |
| SCHEMBL13566019 | 0.78 | CA1 (0.50) | KMT2AMEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL13565952 | 0.78 | PPARA (0.41) | PPARAKMT2APOLBMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |
| US-8299265-B2 | Amine derivatives having NPY Y5 receptor antagonistic activity and the uses thereof | SHIONOGI & CO., LTD. (JP) | 2012-10-30 | — | — | US | disclosed |