Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 9/20 | 0.44 |
| ▸ | PORCN | Q9H237 | 3/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19626366 | 0.84 | PORCN (0.42) | WNT3APORCNTRPA1 | |
| SCHEMBL23416909 | 0.82 | PORCN (0.58) | WNT3APORCNTRPA1 | |
| SCHEMBL19626637 | 0.80 | PORCN (0.51) | WNT3APORCN | |
| SCHEMBL23416896 | 0.79 | PORCN (0.49) | PORCNTRPA1 | |
| SCHEMBL19997369 | 0.79 | PORCN (0.47) | WNT3APORCNTRPA1 | |
| SCHEMBL23416906 | 0.79 | PORCN (0.48) | WNT3APORCN | |
| SCHEMBL19997382 | 0.78 | PORCN (0.40) | PORCNTRPA1 | |
| SCHEMBL21935695 | 0.78 | PORCN (0.46) | PORCNTRPA1 | |
| SCHEMBL19590943 | 0.78 | GAA (0.45) | — | |
| SCHEMBL21413005 | 0.77 | GRM5 (0.37) | PORCNTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9926320-B2 | Purine diones as Wnt pathway modulators | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2018-03-27 | — | — | US | disclosed |