Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PORCN | Q9H237 | 4/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | F10 | P00742 | 2/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19997382 | 0.89 | PORCN (0.40) | PORCNTRPA1RXFP1TP53TRPV4 | |
| SCHEMBL20029975 | 0.86 | MEN1 (0.48) | TRPA1RXFP1TP53SMN1; SMN2 | |
| SCHEMBL22105263 | 0.85 | PORCN (0.40) | PORCNTRPA1TP53TRPV4IDO1 | |
| SCHEMBL22105261 | 0.85 | PSEN1 (0.41) | PORCNRXFP1IDO1F2F10 | |
| SCHEMBL19626536 | 0.85 | MAPT (0.47) | TRPA1TP53SMN1; SMN2 | |
| SCHEMBL19626687 | 0.84 | SMN1; SMN2 (0.42) | RXFP1IDO1MGLLF2F10 | |
| SCHEMBL19626686 | 0.84 | RAB9A (0.52) | TRPA1RXFP1TP53TRPV4IDO1 | |
| SCHEMBL19590943 | 0.84 | GAA (0.45) | SMN1; SMN2 | |
| SCHEMBL19590905 | 0.84 | TRPA1 (0.41) | PORCNTRPA1RXFP1TP53TRPV4 | |
| SCHEMBL22105260 | 0.83 | KMT2A (0.46) | IDO1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2999699-B1 | PURINE DIONES AS WNT PATHWAY MODULATORS | AGENCY SCIENCE TECH & RES (SG) | 2020-04-29 | — | — | EP | disclosed |