Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1406000 | 1.00 | TSHR (0.37) | TSHRHTTHSD17B10MGAMGAA | |
| SCHEMBL1406049 | 1.00 | TSHR (0.37) | TSHRHTTHSD17B10MGAMGAA | |
| SCHEMBL10087479 | 0.90 | TSHR (0.33) | TSHRHTTHSD17B10MGAMGAA | |
| SCHEMBL29133366 | 0.86 | MGAM (0.35) | TSHRHTTHSD17B10MGAMGAA | |
| SCHEMBL1762805 | 0.81 | TSHR (0.39) | TSHRHTTHSD17B10MGAMGAA | |
| SCHEMBL6234988 | 0.80 | LMNA (0.36) | TSHRHSD17B10ALDH1A1MAPT | |
| SCHEMBL395418 | 0.80 | MGAM (0.41) | TSHRHTTHSD17B10MGAMGAA | |
| SCHEMBL6928053 | 0.80 | LMNA (0.36) | TSHRHSD17B10ALDH1A1MAPT | |
| SCHEMBL198108 | 0.80 | MGAM (0.41) | TSHRHTTHSD17B10MGAMGAA | |
| SCHEMBL391523 | 0.80 | MGAM (0.41) | TSHRHTTHSD17B10MGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2327767-B1 | Nitrilases | BASF ENZYMES LLC (US) | 2015-04-29 | — | — | EP | claimed |
| US-9828594-B2 | Nitrilases, nucleic acids encoding them and methods for making and using them | BASF ENZYMES LLC (US) | 2017-11-28 | — | — | US | disclosed |
| CN-104356155-B | Preparation method of (S)-tert-butyldimethylsilyloxy-glutaramate | 浙江新东港药业股份有限公司 | 2017-01-18 | — | — | CN | disclosed |
| US-20160355801-A1 | NITRILASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | VERENIUM CORPORATION | 2016-12-08 | — | — | US | disclosed |
| US-9217164-B2 | Nitrilases, nucleic acids encoding them and methods for making and using them | BASF ENZYMES LLC (US) | 2015-12-22 | — | — | US | disclosed |
| EP-2327766-B1 | Nitrilases | BASF ENZYMES LLC (US) | 2015-12-02 | — | — | EP | disclosed |
| EP-2319919-B1 | Nitrilases | BASF ENZYMES LLC (US) | 2015-08-12 | — | — | EP | disclosed |
| EP-1576108-B1 | NITRILASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | BASF ENZYMES LLC (US) | 2015-07-08 | — | — | EP | disclosed |
| EP-2327767-B1 | Nitrilases | BASF ENZYMES LLC (US) | 2015-04-29 | — | — | EP | disclosed |
| EP-2327765-B1 | Nitrilases | BASF ENZYMES LLC (US) | 2015-04-01 | — | — | EP | disclosed |
| WO-2003106415-A2 | PROCESSES FOR MAKING (R)-ETHYL 4-CYANO-3-HYDROXYBUTYRIC ACID | DIVERSA CORPORATION (US) | 2003-12-24 | — | — | WO | disclosed |
| WO-2003097810-A2 | NITRILASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | DIVERSA CORPORATION (US) | 2003-11-27 | — | — | WO | disclosed |
| US-20030124698-A1 | Which stereoselectively hydrolyze nitrites or cyanohydrins into acids and ammonia | DIVERSA CORPORATION | 2003-07-03 | — | — | US | disclosed |
| US-6586616-B1 | Cyanation and esterification of 3,4-epoxybutyric acid sodium salts to form chemical intermediates for antilipemic agents; by-product inhibition | SAMSUNG FINE CHEMICALS CO., LTD. (KR) | 2003-07-01 | — | — | US | disclosed |
| WO-2003000840-A2 | NITRILASES | DIVERSA CORPORATION (US) | 2003-01-03 | — | — | WO | disclosed |
| EP-1149068-A4 | A PROCESS FOR PREPARING (R)-4-CYANO-3-HYDROXYBUTYRIC ACID ESTER | SAMSUNG FINE CHEMICALS CO LTD (KR) | 2003-01-02 | — | — | EP | disclosed |
| EP-1149068-A1 | A PROCESS FOR PREPARING (R)-4-CYANO-3-HYDROXYBUTYRIC ACID ESTER | Samsung Fine Chemicals Co., Ltd. (KR) | 2001-10-31 | — | — | EP | disclosed |
| US-6140527-A | Process for producing butyric ester derivatives | KANEKA CORPORATION (JP) | 2000-10-31 | — | — | US | disclosed |
| WO-2000046186-A1 | A PROCESS FOR PREPARING (R)-4-CYANO-3-HYDROXYBUTYRIC ACID ESTER | SAMSUNG FINE CHEMICALS CO., LTD (KR) | 2000-08-10 | — | — | WO | disclosed |
| EP-0970947-A1 | PROCESS FOR PRODUCING BUTYRIC ESTER DERIVATIVES | KANEKA CORPORATION (JP) | 2000-01-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030124698-A1 | Which stereoselectively hydrolyze nitrites or cyanohydrins into acids and ammonia | NIT2, DNPH1, ASNS | TSHR 4562/4885HTT 834/4885HSD17B10 1028/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.