Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19998232 | 0.86 | MAPT (0.42) | TSHRMAPTCYP3A4NR3C1PGR | |
| Hydrochloric Acid SCHEMBL11439576 | 0.79 | SMN1; SMN2 (0.57) | MAPTSMN1; SMN2ALDH1A1POLBHPGD | |
| SCHEMBL5716652 | 0.79 | TSHR (0.53) | TSHRMAPTCYP3A4NR3C1PGR | |
| SCHEMBL713941 | 0.78 | TSHR (0.54) | TSHRMAPTCYP3A4NR3C1PGR | |
| SCHEMBL31747006 | 0.78 | TSHR (0.54) | TSHRMAPTCYP3A4NR3C1PGR | |
| SCHEMBL18121900 | 0.77 | HTR6 (0.46) | TSHRMAPTCYP3A4SMN1; SMN2L3MBTL1 | |
| SCHEMBL18138464 | 0.73 | MAPT (0.53) | TSHRMAPTCYP3A4NR3C1PGR | |
| SCHEMBL13344094 | 0.73 | MAPT (0.53) | TSHRMAPTCYP3A4NR3C1PGR | |
| SCHEMBL14713558 | 0.72 | MAPT (0.40) | TSHRMAPTCYP3A4L3MBTL1ALDH1A1 | |
| SCHEMBL22349673 | 0.72 | MEN1 (0.38) | CYP3A4SMN1; SMN2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180086693-A1 | NITROBENZYL DERIVATIVES OF ANTI-CANCER AGENTS | OBI PHARMA, INC. (TW) | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180086693-A1 | NITROBENZYL DERIVATIVES OF ANTI-CANCER AGENTS | TOP2B, TOP2A, NQO1 | TSHR 4231/4885MAPT 4669/4885CYP3A4 857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.