Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.70 |
| ▸ | MAOA | P21397 | 2/20 | 0.63 |
| ▸ | MAOB | P27338 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.55 |
| ▸ | MGAM | O43451 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL72476 | 1.00 | MAPT (0.70) | MAPTMAPK1TDP1MAOAMAOB | |
| SCHEMBL29572230 | 1.00 | MAPT (0.70) | MAPTMAPK1TDP1MAOAMAOB | |
| SCHEMBL72477 | 1.00 | MAPT (0.70) | MAPTMAPK1TDP1MAOAMAOB | |
| SCHEMBL31039664 | 1.00 | MAPT (0.70) | MAPTMAPK1TDP1MAOAMAOB | |
| SCHEMBL12912390 | 1.00 | MAPT (0.70) | MAPTMAPK1TDP1MAOAMAOB | |
| Homopterocarpin SCHEMBL31237481 | 0.92 | MAPT (0.80) | MAPTMAPK1TDP1MAOAMAOB | |
| Homopterocarpin SCHEMBL12998414 | 0.92 | MAPT (0.80) | MAPTMAPK1TDP1MAOAMAOB | |
| Homopterocarpin SCHEMBL29366996 | 0.92 | MAPT (0.80) | MAPTMAPK1TDP1MAOAMAOB | |
| Homopterocarpin SCHEMBL12810250 | 0.92 | MAPT (0.80) | MAPTMAPK1TDP1MAOAMAOB | |
| Homopterocarpin SCHEMBL12810803 | 0.92 | MAPT (0.80) | MAPTMAPK1TDP1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10385061-B2 | Medicarpin, its derivatives, manufacturing method thereof | PHYTOHEALTH CORPORATION (TW) | 2019-08-20 | — | — | US | disclosed |
| CN-107868091-A | Meddigesin, derivatives thereof and preparation method thereof | 怀特生技新药股份有限公司 | 2018-04-03 | — | — | CN | disclosed |
| US-20180086772-A1 | MEDICARPIN, ITS DERIVATIVES, MANUFACTURING METHOD THEREOF | PHYTOHEALTH CORPORATION (TW) | 2018-03-29 | — | — | US | disclosed |
| US-20180086772-A1 | MEDICARPIN, ITS DERIVATIVES, MANUFACTURING METHOD THEREOF | PHYTOHEALTH CORPORATION (TW) | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180086772-A1 | MEDICARPIN, ITS DERIVATIVES, MANUFACTURING METHOD THEREOF | SHARPIN, TIPARP, MYADM | MAPT 4451/4885MAPK1 3474/4885TDP1 2577/4885 |
| US-10385061-B2 | Medicarpin, its derivatives, manufacturing method thereof | SHARPIN, ATP6V1B1, REN | MAPT 4633/4885MAPK1 2736/4885TDP1 3649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.