SCHEMBL72476

SCHEMBL72476

COc1ccc2c(c1)O[C@H]1c3ccc(O)cc3OC[C@@H]21

nearest known ligand 0.77

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 1/20 0.70
▸ MAPK1 P28482 1/20 0.70
▸ TDP1 Q9NUW8 1/20 0.70
▸ MAOA P21397 2/20 0.63
▸ MAOB P27338 2/20 0.63
▸ CYP3A4 P08684 2/20 0.63
▸ PTPN1 P18031 2/20 0.55
▸ MGAM O43451 1/20 0.52
▸ DRD2 P14416 1/20 0.49
▸ DRD3 P35462 1/20 0.49
▸ CYP19A1 P11511 1/20 0.43
▸ ESR1 P03372 2/20 0.42
▸ ESR2 Q92731 2/20 0.42
▸ USP2 O75604 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29572230 1.00 MAPT (0.70) MAPTMAPK1TDP1MAOAMAOB
SCHEMBL72477 1.00 MAPT (0.70) MAPTMAPK1TDP1MAOAMAOB
SCHEMBL31039664 1.00 MAPT (0.70) MAPTMAPK1TDP1MAOAMAOB
SCHEMBL19999732 1.00 MAPT (0.70) MAPTMAPK1TDP1MAOAMAOB
SCHEMBL12912390 1.00 MAPT (0.70) MAPTMAPK1TDP1MAOAMAOB
Homopterocarpin SCHEMBL31237481 0.92 MAPT (0.80) MAPTMAPK1TDP1MAOAMAOB
Homopterocarpin SCHEMBL12998414 0.92 MAPT (0.80) MAPTMAPK1TDP1MAOAMAOB
Homopterocarpin SCHEMBL29366996 0.92 MAPT (0.80) MAPTMAPK1TDP1MAOAMAOB
Homopterocarpin SCHEMBL12810250 0.92 MAPT (0.80) MAPTMAPK1TDP1MAOAMAOB
Homopterocarpin SCHEMBL12810803 0.92 MAPT (0.80) MAPTMAPK1TDP1MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 594 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3346842-B1 STABLE INOCULANT COMPOSITIONS AND METHODS FOR PRODUCING SAME NOVONESIS PLANT BIOSOLUTIONS AS (DK) 2026-03-25 — — EP claimed
US-20240390504-A1 MULTIFUNCTIONAL CONJUGATES E P O S IASIS RES AND DEVELOPMENT LIMITED (CY) 2024-11-28 — — US claimed
CN-118792272-A Licorice isopentenyl transferase and application thereof 中国科学院华南植物园 2024-10-18 — — CN claimed
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 — — US claimed
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2023-03-23 — — US claimed
US-20230027148-A1 MULTIFUNCTIONAL CONJUGATES E.P.O.S IASIS RESEARCH AND DEVELOPMENT LIMITED (CY) 2023-01-26 — — US claimed
US-11560342-B2 Bacillus isolates and uses thereof MONSANTO TECHNOLOGY, LLC (US) 2023-01-24 — — US claimed
WO-2022182523-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2022-09-01 — — WO claimed
WO-2022182527-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2022-09-01 — — WO claimed
WO-2021158575-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2021-08-12 — — WO claimed
CN-102241685-B Method for separating monomer compounds from astragaloside for injection SICHUAN KELUN PHARMACEUTICAL 2013-11-06 — — CN claimed
WO-2013044061-A1 PLANT VIRAL VACCINES AND THERAPEUTICS THE TEXAS A&M UNIVERSITY SYSTEM (US) 2013-03-28 — — WO claimed
CN-102241685-A Method for separating monomer compounds from astragaloside for injection SICHUAN KELUN PHARMACEUTICAL 2011-11-16 — — CN claimed
EP-2295031-A2 Use of pterocarpans as anti-cellulite agents Symrise AG (DE) 2011-03-16 — — EP claimed
US-20110034486-A1 USE OF PTEROCARPANS AS ACTIVE ANTI-CELLULITE INGREDIENTS SYMRISE GMBH & CO., KG (DE) 2011-02-10 — — US claimed
US-20100319084-A1 METABOLIC ENGINEERING FOR PLANT DISEASE RESISTANCE THE SAMUEL ROBERTS NOBLE FOUNDATION 2010-12-16 — — US claimed
US-20090208432-A1 AH Receptor Antagonists SYMRISE GMBH & CO., KG (DE) 2009-08-20 — — US claimed
EP-2035430-A1 6H-BENZOFURO[3,2-C][1]BENZOPYRAN AND [2]BENZOPYRANO [4,3-B][1]BENZOPYRAN DERIVATIVES AND WOOD EXTRACTS OF THESE COMPOUNDS AS ARYL HYDROCARBON RECEPTOR (AHR) ANTAGONISTS FOR THE PREVENTION OF UV-B INDUCED SKIN DAMAGE Symrise GmbH & Co. KG (DE) 2009-03-18 — — EP claimed
WO-2007128725-A1 6H-BENZOFURO[3,2-C] [1]BENZOPYRAN AND [2] BENZOPYRANO [4,3-B] [1]BENZOPYRAN DERIVATIVES AND WOOD EXTRACTS OF THESE COMPOUNDS AS ARYL HYDROCARBON RECEPTOR (AHR) ANTAGONISTS FOR THE PREVENTION OF UV-B INDUCED SKIN DAMAGE SYMRISE GMBH & CO. KG (DE) 2007-11-15 — — WO claimed
US-4704400-A INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS MERCK & CO., INC. (US) 1987-11-03 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090208432-A1 AH Receptor Antagonists AHR, ARNT, HCAR1 MAPT 4785/4885MAPK1 4118/4885TDP1 4418/4885
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES FABP2, FABP4, GUSB MAPT 3926/4885MAPK1 3646/4885TDP1 3469/4885
US-20230027148-A1 MULTIFUNCTIONAL CONJUGATES MKI67, ACP3, CD44 MAPT 3085/4885MAPK1 1828/4885TDP1 4283/4885
US-11560342-B2 Bacillus isolates and uses thereof BLVRB, BROX, GLB1 MAPT 738/4885MAPK1 3187/4885TDP1 2471/4885
US-20240390504-A1 MULTIFUNCTIONAL CONJUGATES MKI67, ACP3, CD44 MAPT 3085/4885MAPK1 1828/4885TDP1 4283/4885
US-20110034486-A1 USE OF PTEROCARPANS AS ACTIVE ANTI-CELLULITE INGREDIENTS FABP4, PLIN1, CPT1B MAPT 4747/4885MAPK1 767/4885TDP1 1491/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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