Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.67 |
| ▸ | MAOB | P27338 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.58 |
| ▸ | MGAM | O43451 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Medicarpin SCHEMBL2812444 | 0.91 | MAOA (0.78) | MAOAMAOBCYP3A4PTPN1MGAM | |
| Demethylmedicarpin SCHEMBL31663447 | 0.91 | MAOA (0.78) | MAOAMAOBCYP3A4PTPN1MGAM | |
| Demethylmedicarpin SCHEMBL29843376 | 0.91 | MAOA (0.78) | MAOAMAOBCYP3A4PTPN1MGAM | |
| SCHEMBL12891390 | 0.84 | MAPT (0.47) | MAOAMAOBCYP3A4PTPN1MGAM | |
| SCHEMBL232991 | 0.84 | CYP3A4 (0.68) | MAOAMAOBCYP3A4PTPN1MGAM | |
| SCHEMBL72476 | 0.83 | MAPT (0.70) | MAOAMAOBCYP3A4PTPN1MGAM | |
| SCHEMBL29572230 | 0.83 | MAPT (0.70) | MAOAMAOBCYP3A4PTPN1MGAM | |
| SCHEMBL19999732 | 0.83 | MAPT (0.70) | MAOAMAOBCYP3A4PTPN1MGAM | |
| SCHEMBL12912390 | 0.83 | MAPT (0.70) | MAOAMAOBCYP3A4PTPN1MGAM | |
| SCHEMBL31039664 | 0.83 | MAPT (0.70) | MAOAMAOBCYP3A4PTPN1MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180086772-A1 | MEDICARPIN, ITS DERIVATIVES, MANUFACTURING METHOD THEREOF | PHYTOHEALTH CORPORATION (TW) | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180086772-A1 | MEDICARPIN, ITS DERIVATIVES, MANUFACTURING METHOD THEREOF | SHARPIN, TIPARP, MYADM | MAOA 1263/4885MAOB 1213/4885CYP3A4 243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.