SCHEMBL20000028

SCHEMBL20000028

C[Si](C)(CCCOCCO)O[Si](C)(C)O[Si](O[Si](C)(C)CCCOCCO)(c1ccccc1)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KCNH3 Q9ULD8 2/20 0.34
TSHR P16473 1/20 0.32
ALDH1A1 P00352 1/20 0.30
RECQL P46063 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20000012 0.94 KCNH3 (0.37) KCNH3TSHRALDH1A1RECQLMEN1
SCHEMBL31412254 0.93 KCNH3 (0.36) KCNH3TSHRALDH1A1RECQLMEN1
SCHEMBL31412255 0.92
SCHEMBL31348329 0.92
SCHEMBL31348371 0.87 GABRA1 (0.31)
SCHEMBL20000019 0.87
SCHEMBL20000027 0.87 NR1H2 (0.32)
SCHEMBL31348313 0.86 KCNH3 (0.30) KCNH3
SCHEMBL20000022 0.85
SCHEMBL20000015 0.85 KCNH3 (0.32) KCNH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180086874-A1 SILICONE-MODIFIED POLYURETHANE-BASED FIBER AND METHOD FOR MANUFACTURING SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-03-29 US disclosed