Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20000013 | 0.94 | NR1H2 (0.35) | NR1H2NR1H3MGAMESR1ESR2 | |
| SCHEMBL12546022 | 0.92 | NR1H2 (0.34) | NR1H2NR1H3MGAMESR1ESR2 | |
| SCHEMBL31412255 | 0.88 | — | — | |
| SCHEMBL31348329 | 0.88 | — | — | |
| SCHEMBL20000028 | 0.87 | KCNH3 (0.34) | — | |
| SCHEMBL20000025 | 0.86 | — | — | |
| SCHEMBL20000034 | 0.84 | HDAC3 (0.32) | — | |
| SCHEMBL676715 | 0.84 | MAOA (0.31) | — | |
| SCHEMBL20000023 | 0.84 | NR1H2 (0.33) | NR1H2NR1H3 | |
| SCHEMBL31348371 | 0.83 | GABRA1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180086874-A1 | SILICONE-MODIFIED POLYURETHANE-BASED FIBER AND METHOD FOR MANUFACTURING SAME | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2018-03-29 | — | — | US | disclosed |