SCHEMBL20000082

SCHEMBL20000082

Cc1c(N)c(C)c(S(N)(=O)=O)c(C)c1N

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 1/20 0.46
CA1 P00915 13/20 0.38
CA2 P00918 12/20 0.38
CA7 P43166 7/20 0.38
CA12 O43570 6/20 0.38
CA13 Q8N1Q1 3/20 0.38
APEX1 P27695 2/20 0.37
CYP2C19 P33261 1/20 0.37
CA9 Q16790 6/20 0.33
CA4 P22748 4/20 0.33
CA3 P07451 2/20 0.33
CA6 P23280 2/20 0.33
CA5A P35218 2/20 0.33
CA5B Q9Y2D0 2/20 0.33
POLB P06746 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CYP2C9 P11712 1/20 0.32
CA14 Q9ULX7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24812540 0.89 KDM4E (0.41) KDM4EALDH1A1CA1CA2CA7
SCHEMBL21135674 0.80 KDM4E (0.40) KDM4EALDH1A1CA1CA2CA7
SCHEMBL1694754 0.79 CA1 (0.43) KDM4EALDH1A1CA1CA2CA7
SCHEMBL21135675 0.79 KDM4E (0.39) KDM4EALDH1A1CA1CA2CA7
SCHEMBL21135679 0.77 KDM4E (0.38) KDM4EALDH1A1CA1CA2CA7
SCHEMBL1271356 0.76 ALDH1A1 (0.34) KDM4EALDH1A1POLBTDP1L3MBTL1
SCHEMBL29044879 0.76 KDM4E (0.34) KDM4EALDH1A1
SCHEMBL4350640 0.76 ALDH1A1 (0.34) KDM4EALDH1A1POLBTDP1L3MBTL1
SCHEMBL4350644 0.74 TTR (0.34) KDM4EALDH1A1TDP1LMNA
SCHEMBL28340716 0.74 ALDH1A1 (0.33) KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11806661-B2 Polymer and method for producing the same, gas separation membrane, gas separation module, and gas separation apparatus using the polymer, and m-phenylenediamine compound FUJIFILM CORPORATION (JP) 2023-11-07 US disclosed
US-11806661-B2 Polymer and method for producing the same, gas separation membrane, gas separation module, and gas separation apparatus using the polymer, and m-phenylenediamine compound FUJIFILM CORPORATION (JP) 2023-11-07 US disclosed
US-20210394113-A1 POLYMER AND METHOD FOR PRODUCING THE SAME, GAS SEPARATION MEMBRANE, GAS SEPARATION MODULE, AND GAS SEPARATION APPARATUS USING THE POLYMER, AND m-PHENYLENEDIAMINE COMPOUND FUJIFILM CORPORATION (JP) 2021-12-23 US disclosed
US-10974207-B2 Gas separation membrane, gas separation membrane module, and gas separation device FUJIFILM CORPORATION (JP) 2021-04-13 US disclosed
WO-2021014821-A1 M-PHENYLENEDIAMINE COMPOUND, POLYMER AND METHOD FOR PRODUCING SAME, GAS SEPARATION MEMBRANE USING THIS POLYMER, GAS SEPARATION MODULE AND GAS SEPARATION APPARATUS 富士フイルム株式会社 2021-01-28 WO disclosed
US-10717706-B2 M-phenylenediamine compound and method for producing polymer compound using same FUJIFILM CORPORATION (JP) 2020-07-21 US disclosed
US-10537859-B2 Gas separation membrane, gas separation module, gas separation device, gas separation method, and polyimide compound FUJIFILM CORPORATION (JP) 2020-01-21 US disclosed
US-20190177270-A1 NOVEL M-PHENYLENEDIAMINE COMPOUND AND METHOD FOR PRODUCING POLYMER COMPOUND USING SAME FUJIFILM CORPORATION (JP) 2019-06-13 US disclosed
US-20190176081-A1 GAS SEPARATION MEMBRANE, GAS SEPARATION MODULE, GAS SEPARATION DEVICE, GAS SEPARATION METHOD, AND POLYIMIDE COMPOUND FUJIFILM CORPORATION (JP) 2019-06-13 US disclosed
US-20190091635-A1 GAS SEPARATION MEMBRANE, GAS SEPARATION MEMBRANE MODULE, AND GAS SEPARATION DEVICE FUJIFILM CORPORATION (JP) 2019-03-28 US disclosed
US-20190076777-A1 GAS SEPARATION MEMBRANE, GAS SEPARATION MEMBRANE MODULE, AND GAS SEPARATION DEVICE FUJIFILM CORPORATION (JP) 2019-03-14 US disclosed
US-20180085716-A1 GAS SEPARATION MEMBRANE, GAS SEPARATION MODULE, GAS SEPARATION DEVICE, GAS SEPARATION METHOD, AND POLYIMIDE COMPOUND FUJIFILM CORPORATION (JP) 2018-03-29 US disclosed
US-20180085716-A1 GAS SEPARATION MEMBRANE, GAS SEPARATION MODULE, GAS SEPARATION DEVICE, GAS SEPARATION METHOD, AND POLYIMIDE COMPOUND FUJIFILM CORPORATION (JP) 2018-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210394113-A1 POLYMER AND METHOD FOR PRODUCING THE SAME, GAS SEPARATION MEMBRANE, GAS SEPARATION MODULE, AND GAS SEPARATION APPARATUS USING THE POLYMER, AND m-PHENYLENEDIAMINE COMPOUND PRMT9, PRMT1, PNMT KDM4E 1786/4885ALDH1A1 2452/4885CA1 1088/4885
US-20190177270-A1 NOVEL M-PHENYLENEDIAMINE COMPOUND AND METHOD FOR PRODUCING POLYMER COMPOUND USING SAME PNMT, PRMT9, HRH3 KDM4E 2711/4885ALDH1A1 3083/4885CA1 4252/4885
US-11806661-B2 Polymer and method for producing the same, gas separation membrane, gas separation module, and gas separation apparatus using the polymer, and m-phenylenediamine compound PRMT9, PRMT1, PNMT KDM4E 1786/4885ALDH1A1 2452/4885CA1 1088/4885
US-10717706-B2 M-phenylenediamine compound and method for producing polymer compound using same PNMT, HRH3, PRMT9 KDM4E 2487/4885ALDH1A1 3143/4885CA1 3970/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.