SCHEMBL20000094

SCHEMBL20000094

CCN(c1ccccc1)c1nc(C)nc(Nc2ccccc2)n1

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.50
MAPT P10636 1/20 0.48
CRHBP P24387 1/20 0.48
CRHR2 Q13324 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
CRHR1 P34998 6/20 0.46
NPY5R Q15761 1/20 0.43
CFTR P13569 2/20 0.43
KCNH3 Q9ULD8 3/20 0.41
TAAR1 Q96RJ0 1/20 0.41
NFKB1 P19838 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9004372 0.85 MAPT (0.50) ALDH1A1MAPTCRHBPCRHR2NPSR1
SCHEMBL8910293 0.79 ALDH1A1 (0.80) ALDH1A1MAPTCRHR1KCNH3TAAR1
SCHEMBL2735960 0.76 CA1 (0.56) ALDH1A1NPSR1CRHR1KCNH3TAAR1
SCHEMBL11936604 0.76 MAPT (0.63) ALDH1A1MAPTNPSR1KCNH3TAAR1
SCHEMBL13752166 0.76 MAPT (0.73) ALDH1A1MAPTCRHBPCRHR2NPSR1
SCHEMBL115405 0.76 MAPT (0.57) ALDH1A1MAPTNPY5RKCNH3TAAR1
SCHEMBL11795866 0.73 NPSR1 (0.44) ALDH1A1MAPTCRHBPCRHR2NPSR1
SCHEMBL11509348 0.73 ALDH1A1 (0.59) ALDH1A1MAPTNPY5RKCNH3NFKB1
SCHEMBL14264133 0.70 ALDH1A1 (0.66) ALDH1A1MAPTNPSR1NPY5RKCNH3
SCHEMBL14264134 0.70 ALDH1A1 (0.71) ALDH1A1MAPTNPY5RKCNH3TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180086918-A1 MIXTURES OF REACTIVE DYES AND THEIR USE FOR THE DYING OR PRINTING FIBRE MATERIALS HUNTSMAN INTERNATIONAL LLC 2018-03-29 US disclosed