Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HCN1 | O60741 | 2/20 | 0.46 |
| ▸ | HCN4 | Q9Y3Q4 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CRHR1 | P34998 | 8/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20000094 | 0.85 | ALDH1A1 (0.50) | MAPTCRHBPCRHR2NPSR1CRHR1 | |
| SCHEMBL9004420 | 0.84 | MAPT (0.49) | MAPTCRHBPCRHR2NPSR1HCN1 | |
| SCHEMBL9004390 | 0.79 | MAPT (0.47) | MAPTCRHBPCRHR2NPSR1HCN1 | |
| SCHEMBL13752166 | 0.78 | MAPT (0.73) | MAPTCRHBPCRHR2NPSR1HCN1 | |
| SCHEMBL11507984 | 0.73 | TDP1 (0.52) | MAPTNPSR1TSHRHSD17B10ALDH1A1 | |
| SCHEMBL15100782 | 0.73 | CRHR1 (0.50) | MAPTTSHRHSD17B10CRHR1ALDH1A1 | |
| SCHEMBL9205898 | 0.72 | HCN1 (0.59) | MAPTCRHBPCRHR2NPSR1HCN1 | |
| SCHEMBL9593807 | 0.72 | HCN1 (0.58) | MAPTCRHBPCRHR2NPSR1HCN1 | |
| Iodide SCHEMBL9004425 | 0.71 | HCN1 (0.57) | MAPTCRHBPCRHR2NPSR1HCN1 | |
| SCHEMBL9004423 | 0.70 | ALDH1A1 (0.63) | MAPTCRHBPCRHR2NPSR1HCN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8911509-B2 | Mixtures of fibre-reactive dyes and their use in a method for di- or trichromatic dyeing or printing | HUNTSMAN INTERNATIONAL LLC (US) | 2014-12-16 | — | — | US | disclosed |
| US-20120302486-A1 | Mixtures of Fibre-Reactive Dyes and Their Use in a Method for Di- or Trichromatic Dyeing or Printing | HUNTSMAN INTERNATIONAL LLC (US) | 2012-11-29 | — | — | US | disclosed |
| US-5574037-A | MODULATED BY SINO-ATRIAL NODE, ANTIISCHEMIC AGENT | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1996-11-12 | — | — | US | disclosed |
| EP-0431856-B1 | Heterocyclic compounds | ZENECA LTD (GB) | 1995-07-12 | — | — | EP | disclosed |
| US-5332737-A | Cardiovascular disorders | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-07-26 | — | — | US | disclosed |
| EP-0431856-A2 | Heterocyclic compounds | ZENECA LIMITED (GB) | 1991-06-12 | — | — | EP | disclosed |