Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | KCNH3 | Q9ULD8 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.52 |
| ▸ | IKBKB | O14920 | 1/20 | 0.52 |
| ▸ | AURKA | O14965 | 1/20 | 0.52 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.52 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11936604 | 0.95 | MAPT (0.63) | MAPTMEN1KMT2AGAAMAPK1 | |
| SCHEMBL4569978 | 0.88 | LMNA (0.71) | MAPTMEN1KMT2AGAAMAPK1 | |
| SCHEMBL19457760 | 0.86 | KCNH3 (0.49) | MAPTMEN1KMT2AGAAMAPK1 | |
| SCHEMBL8908228 | 0.86 | GAA (0.81) | MAPTMEN1KMT2AGAAMAPK1 | |
| SCHEMBL8908232 | 0.86 | NFKB1 (0.75) | MAPTMEN1KMT2AGAAMAPK1 | |
| SCHEMBL23264222 | 0.86 | KCNH3 (0.49) | MAPTMEN1KMT2AGAAMAPK1 | |
| SCHEMBL796156 | 0.86 | BCL6 (0.61) | MAPTMEN1KMT2AGAAMAPK1 | |
| SCHEMBL11236903 | 0.85 | IDH2 (0.64) | MAPTMEN1KMT2AGAAMAPK1 | |
| SCHEMBL8910293 | 0.83 | ALDH1A1 (0.80) | MAPTMEN1KMT2AGAAMAPK1 | |
| SCHEMBL12530695 | 0.83 | KCNH3 (0.70) | MAPTNFKB1KCNH3LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200348595-A1 | COMPOSITION, FILM, AND PRODUCTION METHOD OF PATTERNED SUBSTRATE | JSR CORPORATION (JP) | 2020-11-05 | — | — | US | disclosed |
| US-9790453-B2 | Dye polymer | CONOPCO, INC. (US) | 2017-10-17 | — | — | US | disclosed |
| US-8679195-B2 | Tanning process and tanning composition | CLARIANT FINANCE (BVI) LIMITED (VG) | 2014-03-25 | — | — | US | disclosed |
| US-8318935-B2 | Organic compounds 75074 | NOVARTIS AG (CH) | 2012-11-27 | — | — | US | disclosed |
| US-8318935-B2 | Organic compounds 75074 | NOVARTIS AG (CH) | 2012-11-27 | — | — | US | disclosed |
| US-8188273-B2 | Insecticidal (1,3,5)-triazinyl phenyl hydrazones | DOW AGROSCIENCES, LLC. (US) | 2012-05-29 | — | — | US | disclosed |
| US-20120058357-A1 | Tanning Process and Tanning Composition | CLARIANT FINANCE (BVI) LIMITED (VG) | 2012-03-08 | — | — | US | disclosed |
| US-20120040837-A1 | INSECTICIDAL (1,3,5)-TRIAZINYL PHENYL HYDRAZONES | DOW AGROSCIENCES LLC (US) | 2012-02-16 | — | — | US | disclosed |
| US-8067588-B2 | Insecticidal (1,3,5)-triazinyl phenyl hydrazones | DOW AGROSCIENCES LLC (US) | 2011-11-29 | — | — | US | disclosed |
| EP-2332933-A1 | Epithelial sodium channel (ENaC) inhibitors | Novartis AG (CH) | 2011-06-15 | — | — | EP | disclosed |
| US-20100105660-A1 | ORGANIC COMPOUNDS75074 | NOVARTIS AG (CH) | 2010-04-29 | — | — | US | disclosed |
| US-20100105660-A1 | ORGANIC COMPOUNDS75074 | NOVARTIS AG (CH) | 2010-04-29 | — | — | US | disclosed |
| US-20090093481-A1 | INSECTICIDAL (1,3,5)-TRIAZINYL PHENYL HYDRAZONES | DOW AGROSCIENCES LLC (US) | 2009-04-09 | — | — | US | disclosed |
| US-20090041938-A1 | MIXTURES OF FIBRE REACTIVE DYES PRODUCTION AND USE THEREOF | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 2009-02-12 | — | — | US | disclosed |
| WO-2008135557-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2008-11-13 | — | — | WO | disclosed |
| US-20080227785-A1 | 2,4,6-TRIAMINO-1,3,5-TRIAZINE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2008-09-18 | — | — | US | disclosed |
| US-7425222-B2 | Process for improving the sun protection factor of cellulosic fibre material | CIBA SPECIALTY CHEMICALS CORP. (US) | 2008-09-16 | — | — | US | disclosed |
| US-7375222-B2 | 2,4,6-Triamino-1,3,5-triazine derivative | ASTELLAS PHARMA INC. (JP) | 2008-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090093481-A1 | INSECTICIDAL (1,3,5)-TRIAZINYL PHENYL HYDRAZONES | HELZ, API5, CRYZ | MAPT 2948/4885MEN1 3633/4885KMT2A 1091/4885 |
| US-20200348595-A1 | COMPOSITION, FILM, AND PRODUCTION METHOD OF PATTERNED SUBSTRATE | FN1, COL1A1, FEM1B | MAPT 1331/4885MEN1 457/4885KMT2A 2395/4885 |
| US-20100105660-A1 | ORGANIC COMPOUNDS75074 | SCNN1A, TRPM4, TRPV4 | MAPT 292/4885MEN1 707/4885KMT2A 4259/4885 |
| US-20120040837-A1 | INSECTICIDAL (1,3,5)-TRIAZINYL PHENYL HYDRAZONES | HELZ, API5, CRYZ | MAPT 2948/4885MEN1 3633/4885KMT2A 1091/4885 |
| US-20080227785-A1 | 2,4,6-TRIAMINO-1,3,5-TRIAZINE DERIVATIVE | KCNT1, KCNMA1, KCNJ2 | MAPT 158/4885MEN1 2356/4885KMT2A 274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.