Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29960028 | 1.00 | ALDH1A1 (0.53) | ALDH1A1CYP3A4TSHRALOX15L3MBTL1 | |
| SCHEMBL5718554 | 0.92 | TSHR (0.52) | ALDH1A1CYP3A4TSHRALOX15L3MBTL1 | |
| Nitrobenzene SCHEMBL10937158 | 0.87 | TSHR (0.49) | ALDH1A1CYP3A4TSHRALOX15MAPK1 | |
| SCHEMBL9464332 | 0.85 | ALDH1A1 (0.62) | ALDH1A1CYP3A4TSHRALOX15L3MBTL1 | |
| SCHEMBL4368022 | 0.84 | GPR35 (0.54) | ALDH1A1CYP3A4TSHRALOX15RECQL | |
| SCHEMBL348272 | 0.84 | TSHR (0.59) | ALDH1A1CYP3A4TSHRALOX15L3MBTL1 | |
| SCHEMBL11219818 | 0.84 | TSHR (0.59) | ALDH1A1CYP3A4TSHRALOX15L3MBTL1 | |
| SCHEMBL30578459 | 0.84 | TSHR (0.59) | ALDH1A1CYP3A4TSHRALOX15L3MBTL1 | |
| SCHEMBL9652342 | 0.82 | TSHR (0.57) | ALDH1A1CYP3A4TSHRALOX15L3MBTL1 | |
| SCHEMBL10266188 | 0.82 | GPR35 (0.52) | ALDH1A1CYP3A4TSHRALOX15RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 412 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1437123-B2 | COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME | L'ORÉAL (FR) | 2017-11-08 | — | — | EP | claimed |
| EP-0999823-B2 | COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME | OREAL (FR) | 2011-10-05 | — | — | EP | claimed |
| EP-1666095-B1 | Composition for simultaneous colouring and decolouring of keratinic fibers comprising a meta substituted o-nitroaniline | OREAL (FR) | 2010-05-19 | — | — | EP | claimed |
| US-7452386-B2 | Composition for bleaching and simultaneously dyeing keratin fibers, comprising meta-substituted ortho-nitroaniline | L'OREAL S.A. (FR) | 2008-11-18 | — | — | US | claimed |
| EP-1437123-B1 | COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME | OREAL (FR) | 2007-06-06 | — | — | EP | claimed |
| US-20060191080-A1 | Composition for bleaching and simultaneously dyeing keratin fibers, comprising meta-substituted ortho-nitroaniline | L'OREAL S.A. (FR) | 2006-08-31 | — | — | US | claimed |
| EP-1666095-A1 | Composition for simultanesou colouring and decolouring of keratinic fibers comprising a meta substituted o-nitroaniline | Societe L'Oreal S.A. (FR) | 2006-06-07 | — | — | EP | claimed |
| EP-1437123-A1 | COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME | L'OREAL (FR) | 2004-07-14 | — | — | EP | claimed |
| EP-0999823-B1 | COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME | OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| US-6712861-B2 | CATIONIC DIRECT DYE | L'OREAL S.A. (FR) | 2004-03-30 | — | — | US | claimed |
| WO-1994000415-A1 | NOVEL HYDROXYETHYLATED 2-NITRO-P-PHENYLENEDIAMINES AND USE THEREOF FOR DYEING KERATIN FIBRES | L'OREAL (FR) | 1994-01-06 | — | — | WO | claimed |
| WO-1994000414-A1 | HYDROXYPROPYLATED 2-NITRO-P-PHENYLENEDIAMINES, PREPARATION METHOD THEREFOR AND USE THEREOF FOR DYEING KERATIN FIBRES | L'OREAL (FR) | 1994-01-06 | — | — | WO | claimed |
| US-5226924-A | 1,4-DI(MONO- OR POLY) HYDROXYALKYLAMINO-9,10-ANTHRAQUINONES FOR DYEING HUMAN KERATINOUS FIBRES, COSMETIC COMPOSITION CONTAINING THEM IN COMBINATION WITH AZO AND NITROBENZENE DYES, AND HAIR-DYEING PROCESS USING THEM | L'OREAL (FR) | 1993-07-13 | — | — | US | claimed |
| EP-0480829-A1 | Hair dyeing composition containing anthraquinones | L'OREAL (FR) | 1992-04-15 | — | — | EP | claimed |
| US-4985042-A | New substituted metaaminophenols, a process for their preparation, hair-dyeing compositions containing them and a hair-dyeing process | L'OREAL (FR) | 1991-01-15 | — | — | US | claimed |
| US-4954131-A | Substituted metaaminophenols, a process for their preparation, hair-dyeing compositions containing them and a hair-dyeing process | L'OREAL (FR) | 1990-09-04 | — | — | US | claimed |
| US-4863480-A | OXIDATION COLOR DYES | THE FRENCH JOINT STOCK COMPANY "L'OREAL" (FR) | 1989-09-05 | — | — | US | claimed |
| US-4511360-A | Dyeing compositions based on oxidation dyestuff precursors and on nitro benzene dyestuffs and their use for dyeing keratin fibres | L'OREAL (FR) | 1985-04-16 | — | — | US | claimed |
| US-4324553-A | OXIDATION COLOR DYES | L'OREAL (FR) | 1982-04-13 | — | — | US | claimed |
| US-4323360-A | Dyeing compositions for hair which contain 2,4-diamino-butoxybenzene and/or a salt thereof as the coupling agent | L'OREAL (FR) | 1982-04-06 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060191080-A1 | Composition for bleaching and simultaneously dyeing keratin fibers, comprising meta-substituted ortho-nitroaniline | KRT18, NOX4, NOX5 | ALDH1A1 1918/4885CYP3A4 2229/4885TSHR 4396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.