Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
| ▸ | DRD3 | P35462 | 3/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24836875 | 0.78 | — | — | |
| SCHEMBL23183267 | 0.67 | — | — | |
| SCHEMBL13154392 | 0.65 | — | — | |
| SCHEMBL172585 | 0.65 | — | — | |
| SCHEMBL24248546 | 0.60 | GLB1 (0.34) | — | |
| SCHEMBL21386850 | 0.57 | NOS3 (0.37) | — | |
| SCHEMBL25118617 | 0.57 | GAA (0.34) | DRD2DRD3DRD4GAA | |
| SCHEMBL12181317 | 0.57 | — | — | |
| SCHEMBL18806994 | 0.57 | — | — | |
| SCHEMBL24772842 | 0.57 | GAA (0.42) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018057576-A1 | DEUTERIUM-SUBSTITUTED PYRIDIN- AND PYRIMIDIN-2-YL-METHYLAMINE COMPOUNDS | AUSPEX PHARMACEUTICALS, INC. (US) | 2018-03-29 | — | — | WO | disclosed |