⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20000771 | 0.78 | DRD2 (0.33) | — | |
| SCHEMBL24835763 | 0.76 | — | — | |
| SCHEMBL13154392 | 0.60 | — | — | |
| SCHEMBL172585 | 0.60 | — | — | |
| SCHEMBL24836090 | 0.58 | HTR1A (0.30) | — | |
| SCHEMBL24448728 | 0.57 | GAA (0.32) | — | |
| SCHEMBL19801473 | 0.57 | GAA (0.35) | — | |
| SCHEMBL23183267 | 0.54 | — | — | |
| SCHEMBL24836115 | 0.54 | — | — | |
| SCHEMBL19961007 | 0.54 | GBA1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002390-A1 | HETEROCYCLIC COMPOUNDS AS TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2 AGONISTS AND METHODS OF USE | AMGEN INC. | 2023-01-05 | — | — | US | disclosed |