Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PER2 | O15055 | 14/20 | 0.46 |
| ▸ | CRY2 | Q49AN0 | 7/20 | 0.46 |
| ▸ | FPR1 | P21462 | 1/20 | 0.45 |
| ▸ | FPR2 | P25090 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20001284 | 0.84 | FPR1 (0.49) | PER2CRY2FPR1FPR2 | |
| SCHEMBL20001261 | 0.80 | FPR1 (0.48) | PER2CRY2FPR1FPR2GRM2 | |
| SCHEMBL10306261 | 0.69 | GRM2 (0.41) | GRM2 | |
| SCHEMBL31196623 | 0.68 | OPRL1 (0.53) | GRM2 | |
| SCHEMBL945263 | 0.68 | GRM5 (0.49) | GRM2 | |
| SCHEMBL12947420 | 0.68 | SLC9A1 (0.53) | GRM2 | |
| SCHEMBL4975027 | 0.67 | GRM2 (0.47) | GRM2 | |
| SCHEMBL434354 | 0.67 | OPRL1 (0.57) | GRM2 | |
| SCHEMBL10057668 | 0.67 | GRM2 (0.46) | GRM2 | |
| SCHEMBL6924461 | 0.67 | KDM4E (0.51) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018054549-A1 | 6-MEMBERED CYCLIC AMINES OR LACTAMES SUBSTITUTED WITH UREA AND PHENYL | Grünenthal GmbH (DE) | 2018-03-29 | — | — | WO | disclosed |