SCHEMBL20001295

SCHEMBL20001295

COc1ccc(C2CC(=O)NCC2NC(=O)OC(C)(C)C)c(F)c1

nearest known ligand 0.66

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FPR1 P21462 20/20 0.66
FPR2 P25090 13/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19988417 1.00 FPR1 (0.66) FPR1FPR2
SCHEMBL21342009 0.92 FPR1 (0.56) FPR1FPR2
SCHEMBL19988711 0.89 FPR1 (0.61) FPR1FPR2
SCHEMBL19972289 0.88 FPR1 (0.72) FPR1FPR2
SCHEMBL19988729 0.86 FPR1 (0.64) FPR1FPR2
SCHEMBL19988367 0.86 FPR1 (0.64) FPR1FPR2
SCHEMBL19988378 0.86 FPR1 (0.64) FPR1FPR2
SCHEMBL12665948 0.85 FPR1 (0.47) FPR1FPR2
SCHEMBL12284519 0.85 FPR1 (0.47) FPR1FPR2
SCHEMBL764604 0.85 FPR1 (0.47) FPR1FPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018054549-A1 6-MEMBERED CYCLIC AMINES OR LACTAMES SUBSTITUTED WITH UREA AND PHENYL Grünenthal GmbH (DE) 2018-03-29 WO disclosed
US-20160009841-A1 DEOXYBENZOIN-DERIVED ANTI-FLAMMABLE POLYMERS UNIVERSITY OF MASSACHUSETTS 2016-01-14 US disclosed