SCHEMBL21342009

SCHEMBL21342009

COc1ccc(C2CNC(=O)CC2NC(=O)OC(C)(C)C)c(F)c1

nearest known ligand 0.56

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FPR1 P21462 19/20 0.56
FPR2 P25090 13/20 0.56
KDM1A O60341 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20001295 0.92 FPR1 (0.66) FPR1FPR2
SCHEMBL19988417 0.92 FPR1 (0.66) FPR1FPR2
SCHEMBL21331949 0.88 FPR1 (0.61) FPR1FPR2
SCHEMBL21341986 0.86 FPR1 (0.54) FPR1FPR2
SCHEMBL21341982 0.83 KDM1A (0.53) FPR1FPR2KDM1A
SCHEMBL21341962 0.83 KDM1A (0.53) FPR1FPR2KDM1A
SCHEMBL21341976 0.83 KDM1A (0.53) FPR1FPR2KDM1A
SCHEMBL21342329 0.81 FPR1 (0.46) FPR1FPR2KDM1A
SCHEMBL19988729 0.80 FPR1 (0.64) FPR1FPR2
SCHEMBL19988367 0.80 FPR1 (0.64) FPR1FPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019170904-A1 PIPERIDINES OR PIPERIDONES SUBSTITUTED WITH UREA AND PHENYL Grünenthal GmbH (DE) 2019-09-12 WO disclosed