Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19989641 | 0.86 | SIGMAR1 (0.36) | SIGMAR1MMP2MMP3KDM4E | |
| SCHEMBL29756641 | 0.83 | SIGMAR1 (0.37) | SIGMAR1MMP2MMP3KDM4E | |
| SCHEMBL19989702 | 0.83 | SIGMAR1 (0.37) | SIGMAR1MMP2MMP3KDM4E | |
| SCHEMBL20025454 | 0.83 | SIGMAR1 (0.37) | SIGMAR1MMP2MMP3KDM4E | |
| SCHEMBL29756593 | 0.81 | — | — | |
| SCHEMBL19989677 | 0.81 | — | — | |
| SCHEMBL28810877 | 0.81 | MMP2 (0.33) | MMP2MMP3GPR119 | |
| SCHEMBL23735021 | 0.79 | SIGMAR1 (0.35) | SIGMAR1MMP2MMP3KDM4E | |
| SCHEMBL29756594 | 0.77 | — | — | |
| SCHEMBL19989649 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180086709-A1 | TETRAHYDROPYRIDINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | DONG-A ST CO., LTD. (KR) | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180086709-A1 | TETRAHYDROPYRIDINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | GALE, UGDH, PGLS | SIGMAR1 1438/4885MMP2 314/4885MMP3 358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.