Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20002041 | 0.79 | SYK (0.39) | — | |
| SCHEMBL16886266 | 0.76 | — | — | |
| SCHEMBL11519913 | 0.74 | — | — | |
| SCHEMBL13127659 | 0.73 | — | — | |
| SCHEMBL191513 | 0.73 | ACHE (0.30) | — | |
| SCHEMBL28709224 | 0.73 | THRB (0.30) | — | |
| SCHEMBL497018 | 0.72 | CA1 (0.34) | — | |
| SCHEMBL22652995 | 0.72 | CA1 (0.31) | — | |
| SCHEMBL10891963 | 0.72 | CYP1A2 (0.30) | — | |
| SCHEMBL13127642 | 0.72 | EPHX1 (0.32) | PDK1PDK2PDK3PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3092229-B1 | PYRROLIDINYL SULFONE DERIVATIVES AND THEIR USE AS ROR GAMMA MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2018-03-28 | — | — | EP | disclosed |