Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20002040 | 0.79 | PDK1 (0.31) | — | |
| SCHEMBL16886262 | 0.79 | SYK (0.34) | SYK | |
| SCHEMBL4569269 | 0.77 | SYK (0.33) | SYK | |
| SCHEMBL12359998 | 0.73 | SYK (0.31) | SYK | |
| SCHEMBL16661986 | 0.73 | SYK (0.31) | SYK | |
| SCHEMBL6003016 | 0.73 | SYK (0.31) | SYK | |
| SCHEMBL13760354 | 0.70 | ALDH1A1 (0.33) | — | |
| SCHEMBL20002224 | 0.69 | RORC (0.34) | SYK | |
| SCHEMBL24780270 | 0.67 | — | — | |
| SCHEMBL9221879 | 0.67 | KAT2B (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3092229-B1 | PYRROLIDINYL SULFONE DERIVATIVES AND THEIR USE AS ROR GAMMA MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2018-03-28 | — | — | EP | disclosed |