Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22662761 | 0.83 | RORC (0.47) | KMT2AMEN1RORCEGFRERBB2 | |
| SCHEMBL16875146 | 0.83 | RORC (0.47) | RORC | |
| SCHEMBL27962645 | 0.81 | KMT2A (0.60) | KMT2AMEN1PAX8GAAL3MBTL1 | |
| SCHEMBL28279324 | 0.80 | RORC (0.48) | KMT2APAX8RORC | |
| SCHEMBL6932111 | 0.76 | KMT2A (0.48) | KMT2AMEN1PAX8GAAL3MBTL1 | |
| SCHEMBL28280482 | 0.75 | RORC (0.42) | KMT2AGAAL3MBTL1RORCALDH1A1 | |
| SCHEMBL16875198 | 0.74 | RORC (0.44) | RORCEGFR | |
| SCHEMBL13811433 | 0.73 | ACHE (0.62) | KMT2AMEN1PAX8GAAL3MBTL1 | |
| SCHEMBL2576334 | 0.73 | GAA (0.54) | KMT2AMEN1GAAALDH1A1LMNA | |
| SCHEMBL4792586 | 0.73 | GAA (0.76) | KMT2AMEN1PAX8GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3092229-B1 | PYRROLIDINYL SULFONE DERIVATIVES AND THEIR USE AS ROR GAMMA MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2018-03-28 | — | — | EP | disclosed |