Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19681564 | 0.85 | DRD2 (0.50) | DRD2KDM1AMAOAMAOBTHRB | |
| SCHEMBL1515026 | 0.84 | DRD2 (0.59) | DRD2KDM1AMAOAMAOBALDH1A1 | |
| SCHEMBL11097112 | 0.84 | ALDH1A1 (0.50) | DRD2KDM1AMAOAMAOBTHRB | |
| SCHEMBL12990367 | 0.84 | ESR2 (0.53) | DRD2KDM1AMAOAMAOBTHRB | |
| SCHEMBL11097109 | 0.84 | ALDH1A1 (0.50) | DRD2KDM1AMAOAMAOBTHRB | |
| SCHEMBL9182181 | 0.82 | DRD2 (0.47) | DRD2KDM1AMAOAMAOBTHRB | |
| SCHEMBL9182176 | 0.82 | DRD2 (0.47) | DRD2KDM1AMAOAMAOBTHRB | |
| SCHEMBL12769099 | 0.79 | ALDH1A1 (0.48) | DRD2MAOATHRBALDH1A1SMN1; SMN2 | |
| SCHEMBL9344648 | 0.79 | DRD2 (0.53) | DRD2KDM1AMAOAMAOBTHRB | |
| SCHEMBL25990680 | 0.79 | DRD2 (0.53) | DRD2KDM1AMAOAMAOBTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2792728-B1 | LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT, AND LIQUID CRYSTAL DISPLAY | DAINIPPON INK & CHEMICALS (JP) | 2018-03-28 | — | — | EP | disclosed |