Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20651374 | 0.77 | ALK (0.46) | EGFR | |
| SCHEMBL27977187 | 0.74 | SLC22A12 (0.45) | EGFR | |
| SCHEMBL20003749 | 0.73 | CCR1 (0.42) | EGFR | |
| SCHEMBL18256873 | 0.73 | NR4A2 (0.38) | EGFR | |
| SCHEMBL736202 | 0.68 | NCF1 (0.50) | — | |
| SCHEMBL30098629 | 0.68 | NCF1 (0.50) | — | |
| SCHEMBL18442600 | 0.64 | CYP1A2 (0.31) | EGFR | |
| SCHEMBL29562545 | 0.63 | — | — | |
| SCHEMBL5700328 | 0.63 | — | — | |
| SCHEMBL26634008 | 0.63 | PGK1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299369-A1 | PYRIDO-AZAHETERECYDIC COMPOUND AND PREPARATION METHOD AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2018-03-28 | — | — | EP | disclosed |