Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 11/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.57 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.57 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | GGT1 | P19440 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL338196 | 0.89 | PTGS2 (0.68) | PTGS2KDM4EHSD17B10ALDH1A1TSHR | |
| SCHEMBL29432883 | 0.89 | PTGS2 (0.68) | PTGS2KDM4EHSD17B10ALDH1A1TSHR | |
| Iodide SCHEMBL30619798 | 0.86 | PTGS2 (0.65) | PTGS2KDM4EHSD17B10ALDH1A1TSHR | |
| Ethylene SCHEMBL28225928 | 0.84 | PTGS2 (0.63) | PTGS2KDM4EHSD17B10ALDH1A1TSHR | |
| SCHEMBL10496464 | 0.82 | PTGS2 (0.61) | PTGS2KDM4EHSD17B10ALDH1A1TSHR | |
| SCHEMBL236191 | 0.80 | CA12 (0.59) | PTGS2KDM4EHSD17B10ALDH1A1TSHR | |
| SCHEMBL29655351 | 0.80 | CA12 (0.59) | PTGS2KDM4EHSD17B10ALDH1A1TSHR | |
| SCHEMBL2044698 | 0.80 | PTGS2 (0.59) | PTGS2KDM4EHSD17B10ALDH1A1TSHR | |
| SCHEMBL459655 | 0.78 | PTGS2 (0.57) | PTGS2KDM4EHSD17B10ALDH1A1TSHR | |
| SCHEMBL26566772 | 0.78 | PTGS2 (0.57) | PTGS2KDM4EHSD17B10ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180085333-A1 | 4-PHENYLBUTYRIC ACID DERIVATIVES | TRUOG PETER (CH) | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180085333-A1 | 4-PHENYLBUTYRIC ACID DERIVATIVES | HTR2B, PAH, HTR1B | PTGS2 166/4885KDM4E 1574/4885HSD17B10 239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.