Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | S100A4 | P26447 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | FGB | P02675 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL897309 | 0.83 | HTR5A (0.43) | MEN1KMT2AUSP2S100A4MAPT | |
| SCHEMBL7809349 | 0.81 | MEN1 (0.38) | MEN1KMT2AUSP2S100A4MAPT | |
| SCHEMBL20366561 | 0.80 | MEN1 (0.38) | MEN1KMT2AUSP2S100A4MAPT | |
| SCHEMBL17448466 | 0.80 | MEN1 (0.38) | MEN1KMT2AUSP2S100A4MAPT | |
| SCHEMBL897425 | 0.79 | TDP1 (0.41) | MEN1KMT2AUSP2S100A4MAPT | |
| SCHEMBL20061137 | 0.73 | S100B (0.38) | KMT2AMAPTLMNAALDH1A1GAA | |
| SCHEMBL20061173 | 0.73 | S100B (0.38) | KMT2AMAPTLMNAALDH1A1GAA | |
| SCHEMBL10158550 | 0.71 | KDM4E (0.53) | MEN1KMT2AUSP2S100A4MAPT | |
| SCHEMBL20445639 | 0.70 | KDM4E (0.46) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL20004206 | 0.68 | ALK (0.38) | MEN1KMT2AALDH1A1GAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2975024-B1 | TETRACYCLIC COMPOUNDS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2018-03-28 | — | — | EP | disclosed |