Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6792870 | 0.92 | ALDH1A1 (0.58) | ALDH1A1PPARGPPARASLC6A2PGR | |
| SCHEMBL6792877 | 0.92 | ALDH1A1 (0.58) | ALDH1A1PPARGPPARASLC6A2PGR | |
| SCHEMBL4007604 | 0.89 | ALDH1A1 (0.58) | ALDH1A1PPARGPPARASLC6A2PGR | |
| SCHEMBL9234482 | 0.87 | LMNA (0.56) | ALDH1A1PPARGPPARASLC6A2PGR | |
| SCHEMBL5182481 | 0.87 | LMNA (0.56) | ALDH1A1PPARGPPARASLC6A2PGR | |
| SCHEMBL28968069 | 0.84 | PSEN1 (0.52) | ALDH1A1PPARGPPARASLC6A2PGR | |
| SCHEMBL6161422 | 0.84 | PPARG (0.46) | ALDH1A1PPARGPPARAPTGS1KMT2A | |
| SCHEMBL2189751 | 0.84 | PPARG (0.46) | ALDH1A1PPARGPPARAPTGS1KMT2A | |
| SCHEMBL6162102 | 0.84 | PPARG (0.46) | ALDH1A1PPARGPPARAPTGS1KMT2A | |
| SCHEMBL1393871 | 0.83 | PTGS1 (0.67) | PPARGPPARASLC6A2PGRADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3515912-B1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NAT RECH SCIENT (FR) | 2020-10-14 | — | — | EP | disclosed |
| WO-2018055316-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-29 | — | — | WO | disclosed |