Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | OXTR | P30559 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20004346 | 0.83 | LMNA (0.43) | LMNAHTTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL21199753 | 0.72 | ALDH1A1 (0.50) | LMNAHTTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL20759997 | 0.72 | MAPT (0.52) | LMNAHTTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL879019 | 0.70 | CYP4F2 (0.68) | LMNAHTTSMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL2624372 | 0.70 | GAA (0.62) | LMNAKDM4EALDH1A1KMT2AHPGD | |
| SCHEMBL10745284 | 0.70 | USP5 (0.51) | LMNAHTTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL9052677 | 0.70 | MMP8 (0.53) | LMNAHTTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL8396219 | 0.69 | SMN1; SMN2 (0.51) | LMNAHTTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL11827932 | 0.69 | USP5 (0.63) | LMNAHTTSMN1; SMN2ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL7951117 | 0.69 | KDM4E (0.50) | LMNAHTTSMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3515912-B1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NAT RECH SCIENT (FR) | 2020-10-14 | — | — | EP | disclosed |
| WO-2018055316-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-29 | — | — | WO | disclosed |