Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | GMNN | O75496 | 1/20 | 0.49 |
| ▸ | RAF1 | P04049 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29963109 | 0.79 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL898742 | 0.79 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL898463 | 0.68 | NPC1 (0.50) | ALDH1A1CYP3A4MAPTRAB9AHPGD | |
| SCHEMBL11821359 | 0.68 | PRMT1 (0.50) | ALDH1A1MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL17434684 | 0.67 | MAOA (0.48) | ALDH1A1MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL20004974 | 0.67 | MIF (0.52) | ALDH1A1MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL29504929 | 0.66 | HPGD (1.00) | ALDH1A1MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL157826 | 0.66 | HPGD (1.00) | ALDH1A1MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL253522 | 0.65 | HPGD (0.78) | ALDH1A1MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL896578 | 0.65 | KDM4E (0.63) | ALDH1A1MEN1KMT2ACYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2975024-B1 | TETRACYCLIC COMPOUNDS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2018-03-28 | — | — | EP | disclosed |