Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL897845 | 0.83 | MAPT (0.40) | MAPTALDH1A1MAPK1KMT2ALMNA | |
| SCHEMBL24675699 | 0.73 | ALOX15 (0.39) | ALDH1A1KMT2ALMNAL3MBTL1ALOX15 | |
| SCHEMBL17434650 | 0.71 | ALK (0.38) | MAPTL3MBTL1 | |
| SCHEMBL897877 | 0.70 | PDE5A (0.40) | ALDH1A1LMNAL3MBTL1ALOX15GAA | |
| SCHEMBL897230 | 0.70 | LMNA (0.47) | MAPTALDH1A1LMNAL3MBTL1TDP1 | |
| SCHEMBL17636127 | 0.70 | MAPT (0.39) | MAPTALDH1A1MAPK1KMT2ARAB9A | |
| SCHEMBL897822 | 0.67 | CNR2 (0.54) | MAPTALDH1A1MAPK1KMT2AMEN1 | |
| SCHEMBL897701 | 0.65 | ALDH1A1 (0.50) | MAPTALDH1A1MAPK1KMT2AMEN1 | |
| SCHEMBL7684319 | 0.64 | MAPT (0.77) | MAPTALDH1A1MAPK1KMT2APOLB | |
| SCHEMBL5240079 | 0.62 | ALDH1A1 (0.51) | MAPTALDH1A1MAPK1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2975024-B1 | TETRACYCLIC COMPOUNDS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2018-03-28 | — | — | EP | disclosed |