Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 5/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 5/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8848023 | 0.84 | APP (0.44) | APPAKR1C3AKR1C2LTB4RLTB4R2 | |
| SCHEMBL20004834 | 0.82 | EPHX2 (0.43) | APPAKR1C3AKR1C2LTB4RLTB4R2 | |
| SCHEMBL29660078 | 0.79 | APP (0.41) | APPAKR1C3AKR1C2LTB4RLTB4R2 | |
| SCHEMBL897783 | 0.79 | APP (0.41) | APPAKR1C3AKR1C2LTB4RLTB4R2 | |
| SCHEMBL28160438 | 0.77 | AKR1C3 (0.46) | APPAKR1C3AKR1C2TLR7 | |
| SCHEMBL24021249 | 0.73 | TLR7 (0.51) | AKR1C3AKR1C2TLR7 | |
| SCHEMBL3497043 | 0.72 | MAPT (0.52) | APPAKR1C3AKR1C2CYP2C9KMT2A | |
| SCHEMBL127737 | 0.72 | ALDH1A1 (0.52) | SLC22A12MEN1KMT2A | |
| SCHEMBL129672 | 0.71 | CYP2C19 (0.53) | APPLTB4RLTB4R2CYP1A2KMT2A | |
| SCHEMBL27986171 | 0.71 | MAPT (0.43) | APPAKR1C3AKR1C2LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2975024-B1 | TETRACYCLIC COMPOUNDS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2018-03-28 | — | — | EP | disclosed |