Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | BCL2 | P10415 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 3/20 | 0.45 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL129671 | 0.86 | CYP2C19 (0.50) | CYP2C19CYP1A2LTB4RLTB4R2CYP4F2 | |
| SCHEMBL1124987 | 0.86 | CYP2C19 (0.50) | CYP2C19CYP1A2LTB4RLTB4R2CYP4F2 | |
| SCHEMBL31477275 | 0.84 | CYP2C19 (0.49) | CYP2C19CYP1A2LTB4RLTB4R2CYP4F2 | |
| SCHEMBL289829 | 0.84 | PPARA (0.59) | CYP2C19CYP1A2CYP4F2CYP4A11 | |
| SCHEMBL15067657 | 0.80 | NPC1 (0.46) | CYP2C19CYP1A2LTB4RLTB4R2CYP4F2 | |
| SCHEMBL15678404 | 0.79 | CYP2C19 (0.50) | CYP2C19CYP1A2BCL2KIF11PTGS2 | |
| SCHEMBL127737 | 0.79 | ALDH1A1 (0.52) | KIF11TP53MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL1643008 | 0.77 | HSD17B1 (0.53) | CYP2C19CYP1A2KIF11MAPTKMT2A | |
| SCHEMBL1653535 | 0.77 | KIF11 (0.45) | CYP2C19KIF11MAPTKMT2ASMN1; SMN2 | |
| Acetic Acid SCHEMBL3077099 | 0.76 | ACP3 (0.56) | MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9714240-B2 | Vinyl autotaxin inhibitor compounds | PHARMAKEA, INC. (US) | 2017-07-25 | — | — | US | disclosed |
| US-8450319-B2 | Pyrrolopyridazinone compound | UBE INDUSTRIES, LTD. (JP) | 2013-05-28 | — | — | US | disclosed |
| EP-1982986-B1 | PYRROLOPYRIDAZINONE COMPOUND AS PDE4 INHIBITOR | UBE INDUSTRIES (JP) | 2012-03-07 | — | — | EP | disclosed |
| WO-2011025565-A1 | MORPHOLINONE COMPOUNDS AS FACTOR IXA INHIBITORS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2011-03-03 | — | — | WO | disclosed |
| US-20110028499-A1 | PHARMACEUTICAL COMBINATION COMPRISING VITAMIN K | SHIONOGI & CO., LTD. (JP) | 2011-02-03 | — | — | US | disclosed |
| US-20090036453-A1 | Pyrrolopyridazinone Compound | UBE INDUSTRIES, LTD. (JP) | 2009-02-05 | — | — | US | disclosed |
| EP-1982986-A1 | PYRROLOPYRIDAZINONE COMPOUND | Ube Industries, Ltd. (JP) | 2008-10-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028499-A1 | PHARMACEUTICAL COMBINATION COMPRISING VITAMIN K | PPARD, PROC, VDR | CYP2C19 302/4885CYP1A2 847/4885BCL2 3386/4885 |
| US-20090036453-A1 | Pyrrolopyridazinone Compound | CBR3, CBR1, CYC1 | CYP2C19 44/4885CYP1A2 84/4885BCL2 1166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.