Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23512613 | 0.94 | HRH3 (0.50) | ALDH1A1PLK1HPGDSMN1; SMN2HRH3 | |
| SCHEMBL3497043 | 0.84 | MAPT (0.52) | ALDH1A1HRH3KMT2AMAPT | |
| SCHEMBL28351374 | 0.83 | PLK1 (0.47) | ALDH1A1PLK1HPGDSMN1; SMN2KIF11 | |
| SCHEMBL55105 | 0.83 | PPARA (0.55) | HRH3KIF11KMT2AMAPTSLC13A5 | |
| SCHEMBL28806244 | 0.82 | ESR1 (0.52) | ALDH1A1HPGDSMN1; SMN2HRH3KMT2A | |
| SCHEMBL7182175 | 0.82 | RXRA (0.54) | ALDH1A1HPGDRXRARXRB | |
| SCHEMBL28175080 | 0.82 | MAPT (0.59) | ALDH1A1PLK1HPGDSMN1; SMN2KIF11 | |
| SCHEMBL127736 | 0.82 | HRH3 (0.43) | HRH3KMT2AMAPTSLC13A5 | |
| SCHEMBL479996 | 0.82 | CES2 (0.46) | ALDH1A1HRH3KMT2AMAPTSLC13A5 | |
| SCHEMBL10975329 | 0.82 | CA1 (0.44) | HRH3KMT2AMAPTSLC13A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112047829-B | Synthesis method of alcaine intermediate 2- (4-ethyl-3-iodophenyl) -2-methylpropanoic acid | 成都艾必克医药科技有限公司 | 2023-05-26 | — | — | CN | claimed |
| CN-109438218-B | Synthesis method of hydrochloric acid neritinib intermediate 2- (4-ethyl-3-iodophenyl) -2-methylpropanoic acid | 成都艾必克医药科技有限公司 | 2021-04-09 | — | — | CN | claimed |
| CN-112047829-A | Synthetic method of hydrochloric acid Alininib intermediate 2- (4-ethyl-3-iodophenyl) -2-methylpropanoic acid | 成都艾必克医药科技有限公司 | 2020-12-08 | — | — | CN | claimed |
| CN-109438218-A | A kind of hydrochloric acid Ai Le replaces the synthetic method of Buddhist nun's intermediate 2- (4- ethyl -3- iodophenyl) -2 Methylpropionic acid | 成都艾必克医药科技有限公司 | 2019-03-08 | — | — | CN | claimed |
| US-20250154135-A1 | M-CHOLINE RECEPTOR AGONIST COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | NANJING GRITPHARMA CO., LTD. (CN) | 2025-05-15 | — | — | US | disclosed |
| CN-119707874-A | Synthesis method of aletinib intermediate 2- (4-ethyl-3-iodophenyl) -2-methylpropanoic acid | 重庆博腾制药科技股份有限公司 | 2025-03-28 | — | — | CN | disclosed |
| EP-4471024-A1 | M-CHOLINE RECEPTOR AGONIST COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Nanjing Gritpharma Co., Ltd. (CN) | 2024-12-04 | — | — | EP | disclosed |
| CN-118679159-A | M-choline receptor agonist compound and preparation method and application thereof | 南京济群医药科技股份有限公司 | 2024-09-20 | — | — | CN | disclosed |
| WO-2023143575-A1 | M-CHOLINE RECEPTOR AGONIST COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 南京济群医药科技股份有限公司 | 2023-08-03 | — | — | WO | disclosed |
| CN-112047829-B | Synthesis method of alcaine intermediate 2- (4-ethyl-3-iodophenyl) -2-methylpropanoic acid | 成都艾必克医药科技有限公司 | 2023-05-26 | — | — | CN | disclosed |
| CN-112047829-B | Synthesis method of alcaine intermediate 2- (4-ethyl-3-iodophenyl) -2-methylpropanoic acid | 成都艾必克医药科技有限公司 | 2023-05-26 | — | — | CN | disclosed |
| US-20230142119-A1 | TETRACYCLIC COMPOUND | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-05-11 | — | — | US | disclosed |
| US-20120083488-A1 | TETRACYCLIC COMPOUND | CHUGAI SEIYAKU KABUSHIKI KAISHA | 2012-04-05 | — | — | US | disclosed |
| US-20120083488-A1 | TETRACYCLIC COMPOUND | CHUGAI SEIYAKU KABUSHIKI KAISHA | 2012-04-05 | — | — | US | disclosed |
| EP-1982986-B1 | PYRROLOPYRIDAZINONE COMPOUND AS PDE4 INHIBITOR | UBE INDUSTRIES (JP) | 2012-03-07 | — | — | EP | disclosed |
| US-20110028499-A1 | PHARMACEUTICAL COMBINATION COMPRISING VITAMIN K | SHIONOGI & CO., LTD. (JP) | 2011-02-03 | — | — | US | disclosed |
| WO-2010143664-A1 | TETRACYCLIC COMPOUND | 中外製薬株式会社 (JP) | 2010-12-16 | — | — | WO | disclosed |
| WO-2010112865-A1 | 5-HT RECEPTOR MODULATING COMPOUNDS | SERODUS AS (NO) | 2010-10-07 | — | — | WO | disclosed |
| US-20090036453-A1 | Pyrrolopyridazinone Compound | UBE INDUSTRIES, LTD. (JP) | 2009-02-05 | — | — | US | disclosed |
| EP-1982986-A1 | PYRROLOPYRIDAZINONE COMPOUND | Ube Industries, Ltd. (JP) | 2008-10-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230142119-A1 | TETRACYCLIC COMPOUND | ALK, TTR, ACVR1 | ALDH1A1 1165/4885PLK1 919/4885HPGD 4633/4885 |
| US-20110028499-A1 | PHARMACEUTICAL COMBINATION COMPRISING VITAMIN K | PPARD, PROC, VDR | ALDH1A1 2371/4885PLK1 1741/4885HPGD 446/4885 |
| US-20120083488-A1 | TETRACYCLIC COMPOUND | ALK, TTR, ACVR1 | ALDH1A1 1165/4885PLK1 919/4885HPGD 4633/4885 |
| US-20250154135-A1 | M-CHOLINE RECEPTOR AGONIST COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | CHRNA7, CHRNA1, CHRNE | ALDH1A1 1811/4885PLK1 2006/4885HPGD 1881/4885 |
| US-20090036453-A1 | Pyrrolopyridazinone Compound | CBR3, CBR1, CYC1 | ALDH1A1 580/4885PLK1 4083/4885HPGD 450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.