Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.50 |
| ▸ | CNR1 | P21554 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20004339 | 0.84 | CNR2 (0.50) | CNR2CNR1CYP2C19TSHRLMNA | |
| SCHEMBL5949383 | 0.76 | CYP2C19 (0.63) | CNR2CNR1CYP2C19TSHRLMNA | |
| SCHEMBL10779746 | 0.76 | CYP2C19 (0.63) | CNR2CNR1CYP2C19TSHRLMNA | |
| SCHEMBL12342177 | 0.75 | CYP2C19 (0.49) | CNR2CNR1CYP2C19TSHRNR1H2 | |
| SCHEMBL10781546 | 0.73 | CYP2C19 (0.59) | CNR2CNR1CYP2C19TSHRLMNA | |
| SCHEMBL4428266 | 0.72 | TSHR (0.70) | CNR2CNR1CYP2C19TSHRLMNA | |
| SCHEMBL51810 | 0.71 | CYP2C19 (0.61) | CNR2CNR1CYP2C19TSHRLMNA | |
| SCHEMBL20004984 | 0.71 | PYCR1 (0.57) | CNR2KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14074811 | 0.71 | CYP2C19 (0.56) | CNR2CNR1CYP2C19TSHRLMNA | |
| SCHEMBL2960872 | 0.71 | CYP2C19 (0.78) | CNR2CYP2C19TSHRLMNANR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3515912-B1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NAT RECH SCIENT (FR) | 2020-10-14 | — | — | EP | disclosed |
| WO-2018055316-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-29 | — | — | WO | disclosed |