SCHEMBL20005036

SCHEMBL20005036

C#Cc1cc(C)cc(F)cnc(C)[nH]1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 1/20 0.33
HRH4 Q9H3N8 1/20 0.33
SNCA P37840 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL888985 0.76
SCHEMBL22537766 0.73 ALDH1A1 (0.35)
SCHEMBL31673167 0.63 AGBL2 (0.41)
SCHEMBL12777890 0.60
SCHEMBL4359016 0.60
SCHEMBL26377782 0.60 ACHE (0.36)
SCHEMBL30405965 0.58
SCHEMBL21597045 0.57 CDK5 (0.37) SNCA
SCHEMBL21263259 0.57 SMN1; SMN2 (0.62) SNCA
SCHEMBL24343915 0.56 PIK3CA (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018055316-A1 COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2018-03-29 WO disclosed