SCHEMBL20005171

SCHEMBL20005171

C#Cc1ccc(CN(CC)CCC(C)F)s1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NR1D1 P20393 1/20 0.32
NR1H3 Q13133 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20004373 0.70 CYP2A6 (0.40)
SCHEMBL18734915 0.67 ALDH1A1 (0.39)
SCHEMBL20005140 0.66 POLB (0.44)
SCHEMBL13185585 0.60 HRH3 (0.41)
SCHEMBL16418080 0.60
SCHEMBL20005132 0.60
SCHEMBL21258212 0.60 CA2 (0.33)
SCHEMBL19994729 0.60 DPP4 (0.42)
SCHEMBL3685914 0.60 ALDH1A1 (0.36)
SCHEMBL12203994 0.59 RIPK1 (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3515912-B1 COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES CENTRE NAT RECH SCIENT (FR) 2020-10-14 EP disclosed
WO-2018055316-A1 COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2018-03-29 WO disclosed