Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 4/20 | 0.47 |
| ▸ | WDR77 | Q9BQA1 | 4/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2113619 | 0.86 | DRD2 (0.53) | RIPK1MAPK14DAODRD2DRD4 | |
| SCHEMBL1362779 | 0.77 | RIPK1 (0.55) | RIPK1DAODRD2DRD4DRD3 | |
| SCHEMBL6994522 | 0.74 | LOXL2 (0.53) | DRD2DRD4DRD3 | |
| SCHEMBL857198 | 0.74 | GLRA3 (0.50) | PRMT5WDR77MEN1KMT2A | |
| SCHEMBL4518152 | 0.74 | HDAC1 (0.49) | PRMT5WDR77NR3C1NR3C2CDK2 | |
| SCHEMBL25230913 | 0.74 | DRD2 (0.50) | RIPK1DAODRD2DRD4DRD3 | |
| SCHEMBL2176426 | 0.74 | LOXL2 (0.52) | RIPK1DAODRD2DRD4DRD3 | |
| SCHEMBL1939638 | 0.74 | DRD2 (0.50) | RIPK1DAODRD2DRD4DRD3 | |
| SCHEMBL13543890 | 0.74 | RIPK1 (0.58) | RIPK1DAODRD2DRD4DRD3 | |
| SCHEMBL17451039 | 0.74 | DRD2 (0.50) | RIPK1DAODRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3515912-B1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NAT RECH SCIENT (FR) | 2020-10-14 | — | — | EP | disclosed |
| WO-2018055316-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-29 | — | — | WO | disclosed |