SCHEMBL20005261

SCHEMBL20005261

Cc1ccc(-c2ccc(-c3cc(C)c(C#Cc4cc(F)c(C#CS(F)(F)(F)(F)F)c(F)c4)c(F)c3)c(F)c2)c(F)c1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.30
AKR1C2 P52895 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20005289 0.87 AKR1C3 (0.33) AKR1C3AKR1C2
SCHEMBL20004795 0.83 GRM5 (0.34) AKR1C3AKR1C2
SCHEMBL19999505 0.82 RARB (0.39)
SCHEMBL20004684 0.82 AKR1C3 (0.35) AKR1C3AKR1C2
SCHEMBL20004915 0.82 PDE3B (0.33) AKR1C3AKR1C2
SCHEMBL20005288 0.81 PDE3B (0.32) AKR1C3AKR1C2
SCHEMBL20005243 0.80 PDE9A (0.33)
SCHEMBL20004824 0.79 KDM1A (0.35) AKR1C3AKR1C2
SCHEMBL20004646 0.78 KDM1A (0.31)
SCHEMBL20004910 0.77 GRM5 (0.33) AKR1C3AKR1C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3299439-A1 LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC Corporation (JP) 2018-03-28 EP disclosed