Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.44 |
| ▸ | ITGAV | P06756 | 7/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 2/20 | 0.38 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.38 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1995408 | 0.88 | ITGB3 (0.41) | ITGB3ITGAVMCL1PPARGPPARD | |
| SCHEMBL2001952 | 0.87 | PPARG (0.52) | ITGB3ITGAVMCL1PPARGPPARD | |
| SCHEMBL2002036 | 0.81 | SRD5A2 (0.55) | PPARDPPARA | |
| SCHEMBL2002039 | 0.81 | SRD5A2 (0.55) | PPARDPPARA | |
| SCHEMBL18258591 | 0.80 | AKR1C3 (0.54) | AKR1C3AKR1C2 | |
| SCHEMBL18258592 | 0.80 | AKR1C3 (0.54) | AKR1C3AKR1C2 | |
| SCHEMBL1998860 | 0.80 | PPARD (0.47) | PPARGPPARDPPARA | |
| SCHEMBL2001227 | 0.80 | NPSR1 (0.47) | MCL1PPARGPPARDPPARA | |
| SCHEMBL2003264 | 0.78 | PPARG (0.47) | ITGB3ITGAVMCL1PPARGPPARD | |
| SCHEMBL2000849 | 0.78 | PPARA (0.42) | ITGB3ITGAVMCL1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7964622-B2 | Indole acetic acid derivatives and their use as pharmaceutical agents | BAYER HEALTHCARE LLC (US) | 2011-06-21 | — | — | US | disclosed |
| US-20090298854-A1 | Indole acetic acid derivatives and their use as pharmaceutical agents | MA XIN | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298854-A1 | Indole acetic acid derivatives and their use as pharmaceutical agents | IDO1, IDO2, AADAT | ITGB3 4684/4885ITGAV 4461/4885MCL1 2673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.