Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 6/20 | 0.54 |
| ▸ | AKR1C2 | P52895 | 6/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | CDC42 | P60953 | 1/20 | 0.54 |
| ▸ | RAC1 | P63000 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18258591 | 1.00 | AKR1C3 (0.54) | AKR1C3AKR1C2PTGS2PTGS1TSHR | |
| SCHEMBL2000849 | 0.83 | PPARA (0.42) | AKR1C3AKR1C2PTGS2PTGS1TSHR | |
| SCHEMBL597518 | 0.81 | HTR2C (0.58) | AKR1C3AKR1C2PTGS2PTGS1TSHR | |
| SCHEMBL1998775 | 0.81 | NPC1 (0.44) | AKR1C3AKR1C2PTGS2PTGS1TSHR | |
| SCHEMBL2002039 | 0.80 | SRD5A2 (0.55) | CYP1A2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL2000563 | 0.80 | ITGB3 (0.44) | AKR1C3AKR1C2 | |
| SCHEMBL2002036 | 0.80 | SRD5A2 (0.55) | CYP1A2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL2002647 | 0.80 | PTGS2 (0.38) | PTGS2KDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL6258605 | 0.80 | HTR2A (0.45) | PTGS2HTR2CSLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL22798770 | 0.79 | SLC6A2 (0.48) | PTGS2TSHRHTR2CSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3098217-B1 | METHOD FOR PRODUCING OPTICALLY ACTIVE CARBOXYLIC ACID ESTER | UNIV TOKYO SCIENCE FOUND (JP) | 2018-04-25 | — | — | EP | disclosed |
| US-9796640-B2 | Method for producing optically active carboxylic acid ester | TOKYO UNIVERSITY OF SCIENCE FOUNDATION (JP) | 2017-10-24 | — | — | US | disclosed |
| US-20170008820-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE CARBOXYLIC ACID ESTER | TOKYO UNIVERSITY OF SCIENCE FOUNDATION (JP) | 2017-01-12 | — | — | US | disclosed |
| EP-3098217-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE CARBOXYLIC ACID ESTER | Tokyo University of Science Foundation (JP) | 2016-11-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170008820-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE CARBOXYLIC ACID ESTER | ADH1A, ALDH1A2, ADH1C | AKR1C3 38/4885AKR1C2 55/4885PTGS2 791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.