SCHEMBL20006152

SCHEMBL20006152

Cn1cc[n+](Cc2ccc(CBr)cc2)c1

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CHKA P35790 9/20 0.34
ACHE P22303 3/20 0.34
BCHE P06276 2/20 0.34
NT5E P21589 1/20 0.32
TRPA1 O75762 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12891425 0.91 CHKA (0.39) CHKAACHEBCHENT5E
Iodide SCHEMBL2527841 0.84 CHKA (0.40) CHKAACHEBCHENT5EALDH1A1
SCHEMBL6398845 0.82 NT5E (0.35) CHKAACHEBCHENT5E
SCHEMBL20843604 0.82 CHKA (0.46) CHKAACHEBCHENT5EALDH1A1
Hydrochloric Acid SCHEMBL6115480 0.82 CHKA (0.46) CHKAACHEBCHENT5EALDH1A1
SCHEMBL667064 0.81 CHKA (0.46) CHKAALDH1A1
Hydrochloric Acid SCHEMBL28638859 0.81 CHKA (0.33) CHKAACHEBCHENT5EALDH1A1
Iodide SCHEMBL13735549 0.81 CA1 (0.43) CHKAACHEBCHENT5EALDH1A1
Iodide SCHEMBL2195240 0.80 CHKA (0.44) CHKAALDH1A1
Hydrochloric Acid SCHEMBL382999 0.80 ALDH1A1 (0.46) CHKAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018056902-A1 IMIDAZOLIUM COMPOUNDS, METHODS OF SYNTHESIS AND USES THEREOF AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2018-03-29 WO disclosed