Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.33 |
| ▸ | CHKA | P35790 | 7/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28054713 | 0.92 | SIGMAR1 (0.31) | CHKABCHEACHESIGMAR1 | |
| SCHEMBL12891425 | 0.89 | CHKA (0.39) | CHKABCHEACHENT5E | |
| Hydrochloric Acid SCHEMBL6115480 | 0.84 | CHKA (0.46) | CHKABCHEACHENT5EKDM4E | |
| Hydrochloric Acid SCHEMBL382999 | 0.82 | ALDH1A1 (0.46) | CHKAKDM4EALDH1A1RAB9A | |
| Iodide SCHEMBL2527841 | 0.82 | CHKA (0.40) | CHKABCHEACHENT5EKDM4E | |
| SCHEMBL6398845 | 0.81 | NT5E (0.35) | CHKABCHEACHENT5E | |
| SCHEMBL20006152 | 0.81 | CHKA (0.34) | CHKABCHEACHENT5EALDH1A1 | |
| SCHEMBL20843604 | 0.81 | CHKA (0.46) | CHKABCHEACHENT5EALDH1A1 | |
| SCHEMBL667064 | 0.80 | CHKA (0.46) | CHKAKDM4EALDH1A1RAB9A | |
| Iodide SCHEMBL13735549 | 0.79 | CA1 (0.43) | CHKABCHEACHENT5EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110526871-B | 1-methyl-3- (4-diacetoxyiodobenzyl) imidazole chloride salt and preparation and application thereof | 浙江工业大学 | 2021-05-11 | — | — | CN | disclosed |